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PRESTO-Tango GPCRome screening (HCA3)
Assay data:1 Tested
SummaryRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Antagonist activity at GPR109b (unknown origin) at 10 uM by aequorin based assay relative to control
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at GPR109b (unknown origin) at 10 uM by aequorin based assay relative to control
Human HCA3 receptor (Hydroxycarboxylic acid receptors)
Assay data:12 Active, 12 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at HCA3 receptor (unknown origin) expressed in CHOK1 cells assessed as ERK1/2 phosphorylation by ELISA
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at HCA3 receptor (unknown origin) expressed in Saccharomyces cerevisiae MMY24 assessed as growth rate of yeast on histidine deficient medium at 100 uM by FUS1-HIS3 reporter gene assay
Assay data:15 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Agonist activity at human HCA3 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation up to 50 uM after 30 mins
Assay data:11 Tested
Agonist activity at human HCA3 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation at 50 uM after 30 mins
Assay data:20 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Agonist activity at human GPR109b assessed as decrease in forskolin-stimulated cAMP production by HTRF assay
Assay data:39 Tested
Agonist activity at human GPR109b
Assay data:6 Active, 5 Activity ≤ 1 µM, 7 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
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