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Inhibition of TG3 (unknown origin) using peptidic FRET quenched probe A101 as substrate and measured by fluorescence-based assay
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Transamidation Assay for Determining Inhibitor Selectivity from US Patent US11472838: "Inhibitors of blood coagulation factor XIII"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
TG Activity Assays from Article 10.1016/j.chembiol.2015.08.013: "Development of Potent and Selective Tissue Transglutaminase Inhibitors: Their Effect on TG2 Function and Application in Pathological Conditions."
Assay data:27 Active, 14 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inactivation of activated human TG3 assessed as rate constant of enzyme inactivation using FRET- quenched A101 as substrate by fluorescence assay
Assay data:2 Tested
Irreversible inhibition of human TGase 3 assessed as ratio of Kinact/Ki using Z-Glu(HMC)-Gly-OH as substrate measured at 20 secs interval over 900 secs by fluorimetric assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Secondary screen TNF readout
Assay data:731 Active, 3462 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
Inhibition of human transglutaminase 3 using ((benzyloxy)carbonyl)-L-glutaminyl-L-serine peptide substrate assessed as Kinh/Ki ratio by GDH coupled assay
Assay data:8 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Inhibition of transglutaminase 3
Assay data:4 Tested
Inhibition of human TGM3
Assay data:1 Tested
Inhibition of thrombin activated human TG3 by fluorescent transamidation assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 69 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
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