BioAssay by Target (List) for Gene (Select 6733) - PubChem BioAssay - NCBI

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Select item 19152251.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000295b SRPK2

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1915225

Summary Related BioAssays by Target

Select item 19149322.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000332a SRPK2

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1914932

Summary Related BioAssays by Target

Select item 19146033.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000743a SRPK2

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1914603

Summary Related BioAssays by Target

Select item 19144984.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000315b SRPK2

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1914498

Summary Related BioAssays by Target

Select item 18511685.

Inhibition of SRPK2 (unknown origin) incubated for 1 hr in presence of ATP by fluorescent plate reader method

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1851168

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18511656.

Inhibition of SRPK2 (unknown origin) incubated for 10 mins in presence of ATP by Kinase-Glo assay

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1851165

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18451327.

Reverse ITC (compound as receptor). Domain start/stop: G62-S699

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1845132

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18354858.

SRPK2 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1835485

Summary Related BioAssays by Target

Select item 18351639.

SRPK2(h) Kinase panel

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1835163

Summary Related BioAssays by Target

Select item 183445710.

Cellular target engagement assay with: SRPK2

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1834457

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183445611.

Cellular target engagement assay with: SRPK2

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

AID:: 1834456

Summary Related BioAssays by Target

Select item 183432912.

Inhibition of SRPK2 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1834329

Summary PubMed Citation Related BioAssays by Target

Select item 180567413.

Inhibition Assay from US Patent US11066363: "Substituted 6,11-dihydro-5H-benzo[B]carbazoles as inhibitors of ALK and SRPK"

Source:: BindingDB

Protein Targets:: SRSF protein kinase 1; ...
Total:: 2

Assay data:12 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested

AID:: 1805674

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179434714.

KinomeScan assay: inhibition of SRPK2

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Active, 108 Tested

AID:: 1794347

Summary Compounds, Active Related BioAssays by Target

Select item 179382015.

SRPK2(SRP2IGRL) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793820

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179353516.

SRPK2(SRP2IGRL) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793535

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179324117.

SRPK2(SRP2IGRL) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793241

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179285618.

SRPK2(h) Eurofins kinase panel

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1792856

Summary Related BioAssays by Target

Select item 179247219.

SRPK2 ProQinase selectivity panel

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1792472

Summary Related BioAssays by Target

Select item 179157120.

SRPK2 Kinase activity screen

Source:: ChEMBL

Protein Target:: SRSF protein kinase 2

Assay data:1 Tested

AID:: 1791571

Summary Related BioAssays by Target

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Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (18)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (14)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (18)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (40)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (125)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (44)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (92)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (74)
BioAssays deposited by other experimentalists

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