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EMSA assay for RPA-DNA inhibition activity from US Patent US10774063: "Materials and method for inhibiting replication protein A and uses thereof"
Assay data:12 Tested
SummaryRelated BioAssays by Target
In Vitro Assay from US Patent US9533969: "Materials and method for inhibiting replication protein A and uses thereof"
Assay data:6 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Binding affinity to RPA70 (unknown origin) by FITC-labeled probe based fluorescence polarization anisotropy
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to human recombinant RPA70 expressed in Escherichia coli BL21 using FPA by tryptophan fluorescence quenching assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of GST-tagged X-rhodamine-labelled p53TAD2 binding to human recombinant RPA70 expressed in Escherichia coli BL21 by fluorescence anisotropy competition assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Displacement of FITC-ATRIP/FITC-ATRIP2 peptide probe from RPA70N protein (unknown origin) at 500 uM incubated for 1 hr by fluorescence polarization anisotropy assay
Assay data:9 Tested
Binding affinity to RPA70N protein (unknown origin) incubated for 1 hr using FITC-ATRIP/FITC-ATRIP2 peptide probe by fluorescence polarization anisotropy assay
Assay data:34 Active, 3 Activity ≤ 1 nM, 47 Activity ≤ 1 µM, 47 Tested
Binding affinity to RPA70N protein (unknown origin) by HSQC NMR-based titration method
Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Inhibition of purified full length RPA70 (unknown origin) binding to radiolabelled single strand DNA at 0.1 to 100 uM after 20 mins by electrophoretic mobility shift assay
Selectivity ratio of Kd for recombinant human RPA70 A/B region (181 to 422 amino acids) expressed in Escherichia coli Rosetta to Kd for human RPA70 N-terminal domain (1 to 120 amino acids) expressed in Escherichia coli BL21-DE3
Binding affinity to recombinant human RPA70 A/B region (181 to 422 amino acids) expressed in Escherichia coli Rosetta by fluorescence polarization anisotropy assay
Assay data:1 Active, 2 Tested
Binding affinity to recombinant human RPA70 N-terminal domain (1 to 120 amino acids) expressed in Escherichia coli BL21-DE3 by fluorescence polarization anisotropy assay
Assay data:19 Active, 8 Activity ≤ 1 µM, 42 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Binding affinity to RPA70N (1 to 120) site1 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy
Assay data:4 Tested
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