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Agonist activity at NPRA in human HeLa cells assessed as increased cGMP formation at 1 uM incubated for 30 mins in presence of IBMX by ELISA
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at NPRA in human HeLa cells assessed as increased cGMP formation at 10 uM incubated for 30 mins in presence of IBMX by ELISA
Assay data:10 Tested
SummaryPubMed CitationRelated BioAssays by Target
Atrial Natriuretic Factor (ANF) Eurofins-Panlabs radioligand binding assay
Assay data:5 Tested
SummaryRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Agonist activity at human NPR-A expressed in CHO cells assessed as increase in intracellular cGMP accumulation after 30 mins in presence of 1-methyl-3-isobutylxanthine by radioimmunoassay
Assay data:14 Active, 1 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 21 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count method
Assay data:2 Active, 1 Activity ≤ 1 nM, 25 Activity ≤ 1 µM, 25 Tested
Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassay
Assay data:6 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 8 Tested
Assay data:25 Active, 1 Activity ≤ 1 nM, 22 Activity ≤ 1 µM, 25 Tested
Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot CMLD screen
Assay data:19 Active, 301 Activity ≤ 1 µM, 1838 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen
Assay data:33 Active, 19 Activity ≤ 1 µM, 1280 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Natriuretic polypeptide receptor (hNpr1) antagonism - Primary qHTS
Assay data:1232 Active, 91 Activity ≤ 1 µM, 76369 Tested
Natriuretic polypeptide receptor (hNpr1) antagonism - Confirmation
Assay data:1067 Active, 5 Activity ≤ 1 µM, 1408 Tested
Human Guanylyl cyclase-A (Receptor Guanylyl Cyclase (RGC) family)
Assay data:11 Active, 11 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
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