Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Safety47 Scan (DiscoverX - Eurofins)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Histamine H2 Eurofins Panlabs panel
H2/APT/HS Eurofins SafetyScreen44 (BI)
Binding affinity towards human HRH2 in an in vitro assay with cellular components measured by membrane filtration
Assay data:61 Active, 32 Activity ≤ 1 µM, 283 Tested
Agonist activity at human HRH2 in an in vitro cell-based assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:12 Active, 7 Activity ≤ 1 µM, 1115 Tested
Inhibition of histamine h2 (unknown origin)
Assay data:2 Tested
Displacement of [3H]tiotidine from recombinant human histamine H2 receptor expressed in CHO-K1 cell membrane at 1 uM incubated for 45 mins by Scintillation counter analysis relative to control
Displacement of [125I]APT from human recombinant histamine H2 receptor at 10 uM after 120 mins by scintillation counting analysis relative to control
Assay data:3 Tested
Antagonist potency at recombinant human histamine H2 receptor expressed in HEK293 cells assessed as inhibition of histamine-induced cAMP accumulation
Assay data:1 Active, 1 Tested
Antagonist activity at histamine H2 receptor (unknown origin) assessed as inhibition constant
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of histamine H2 receptor (unknown origin) at 10 uM
Selectivity interaction (GPCR panel (PDSP screen)) EUB0000307b HRH2
SummaryCompounds, ActiveRelated BioAssays by Target
Selectivity interaction (PRESTO-Tango GPCR-ome screening) EUB0000539a HRH2
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on