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Inhibition of mouse Slc26a4-mediated Cl-/ I- exchange at 10 uM measured by cell-based fluorescence assay
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated kinetics of CI7HCO3(-) exchange by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with NO3(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with I(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with SCN(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of mouse slc26a4 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exchange at 10 uM preincubated for 10 mins followed by NaI-substituted PBS addition and measured by YFP-based fluorescence assay
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mins by fluorescence based assay
Assay data:5 Active, 17 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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