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Activation of TrkB receptor in Swiss Webster mouse immature cerebrocortical neuron assessed as phosphorylation of TrkB at Tyr516 residue at 30 nM incubated for 30 mins in presence of NMDAR antagonist MK-801 by western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of TrkB receptor in Swiss Webster mouse immature cerebrocortical neuron assessed as phosphorylation of TrkB at Tyr516 residue at 30 nM incubated for 30 mins in presence of VGSC blocker TTX by western blot analysis
Activation of TrkB receptor in Swiss Webster mouse immature cerebrocortical neuron assessed as phosphorylation of TrkB at Tyr516 residue at 30 nM incubated for 30 mins by western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activation of TrkB receptor in Swiss Webster mouse immature cerebrocortical neuron assessed as increase in neurite outgrowth at 30 nM incubated for 24 hrs in the presence of TrkB inhibitor K252a by DiI dye based microscopic analysis
Inhibition of TrkB in mouse MG87 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid assessed as reduction in ERK1/ERK2 phosphorylation at 0.01 to 1 uM after 5 mins in presence of BDNF by Western blot analysis
Assay data:3 Active, 3 Tested
Inhibition of TrkB in mouse MG87 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid assessed as reduction in Akt phosphorylation at 0.01 to 1 uM after 5 mins in presence of BDNF by Western blot analysis
Inhibition of TrkB phosphorylation in mouse MG87 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid at 1 uM after 5 mins in presence of BDNF by Western blot analysis
Agonist activity at TrkB receptor in Swiss mouse primary cortical neurons transfected with AAV2 Tdtomato assessed as increase in dendritic arborization at 100 nM after 72 hrs by confocal microscopic analysis
Agonist activity at TrkB receptor in Swiss mouse primary cortical neurons assessed as increase in PSD95 expression after 72 hrs by Western blot analysis
Agonist activity at TrkB receptor in Swiss mouse primary cortical neurons assessed as increase in MAP2 expression after 72 hrs by Western blot analysis
Agonist activity at TrkB receptor in Swiss mouse primary cortical neurons assessed as increase in TrkB phosphorylation at Y705 residue after 15 mins by Western blot analysis
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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