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KAT-7 Enzyme Assay from US Patent US11685732: "MYST family histone acetyltransferase inhibitors"
Assay data:336 Active, 407 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Kat7 Assay from US Patent US11492346: "Benzisoxazole sulfonamide derivatives"
Assay data:116 Active, 89 Activity ≤ 1 µM, 120 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of MYST2 (unknown origin) using Histone H3 substrate at 1 uM relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MYST2 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assay
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of KAT7 (unknown origin)
Inhibition of MYST2 (unknown origin)
Assay data:2 Tested
Inhibition of KAT7 (unknown origin) assessed as reduction in H3K9ac acetylation at 10 uM relative to control
Inhibition of KAT7 (unknown origin) assessed as reduction in H3K14ac acetylation at 10 uM relative to control
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of HBO1 (unknown origin) using N-terminal histone H3 substrate at 100 uM by fluorescence assay in presence of [3H]acetyl-CoA relative to control
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Secondary screen TNF readout
Assay data:731 Active, 3462 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
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