Homo sapiens HECT domain and ankyrin repeat containing E3 ubiquitin pr - Nucleotide

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Emerging role and mechanism of HACE1 in the pathogenesis of neurodegenerative diseases: A promising target. [Biomed Pharmacother. 2024]
Emerging role and mechanism of HACE1 in the pathogenesis of neurodegenerative diseases: A promising target.
Zang C, Liu H, Ning J, Chen Q, Jiang Y, Shang M, Yang Y, Ma J, Dong Y, Wang J, et al. Biomed Pharmacother. 2024 Mar; 172:116204. Epub 2024 Feb 15.
HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2. [Aging (Albany NY). 2023]
HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2.
Yin P, Wu Y, Long X, Zhu S, Chen S, Lu F, Lin K, Xu J. Aging (Albany NY). 2023 Dec 6; 15(23):13888-13900. Epub 2023 Dec 6.
Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization. [Adv Sci (Weinh). 2023]
Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Singh S, Machida S, Tulsian NK, Choong YK, Ng J, Shankar S, Liu Y, Chandiramani KV, Shi J, Sivaraman J. Adv Sci (Weinh). 2023 Sep; 10(27):e2207672. Epub 2023 Aug 3.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the HACE1 gene.
RefSeq protein product
See the reference protein sequence for E3 ubiquitin-protein ligase HACE1 isoform d (NP_001337486.1).

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Protein sequence from Nucleotide coding region
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Homo sapiens chromosome X, GRCh38.p14 Primary Assembly
Homo sapiens chromosome X, GRCh38.p14 Primary Assembly
gi|568815575|gnl|ASM:GCF_000001305| |NC_000023.11||gpp|GPC_000001315.1||gnl|NCBI_GENOMES|23

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Nucleotide