A decreased magnitude of the sensory perception of sound.

A generalized disorder of peripheral nerves.

Persistent deficits in social interaction and communication and interaction as well as a markedly restricted repertoire of activity and interest as well as repetitive patterns of behavior.

A severe delay in the achievement of motor or mental milestones in the domains of development of a child.

A moderate delay in the achievement of motor or mental milestones in the domains of development of a child.

Underdevelopment of the malar prominence of the jugal bone (zygomatic bone in mammals), appreciated in profile, frontal view, and/or by palpation.

Greater than average forward and/or lateral protrusion of the supraorbital portion of the frontal bones.

Distance between nasal base and midline upper lip vermilion border more than 2 SD below the mean. Alternatively, an apparently decreased distance between nasal base and midline upper lip vermilion border.

Lack or loss of the soft tissues between the zygomata and mandible.

Deposition of calcium salts in subcutaneous tissue (i.e., the the lowermost layer of the integument).

Meeting of the medial eyebrows in the midline.

A cataract that occurs congenitally as the result of a developmental defect, in contrast to the majority of cataracts that occur in adulthood as the result of degenerative changes of the lens.

A misalignment of the eyes so that the visual axes deviate from bifoveal fixation. The classification of strabismus may be based on a number of features including the relative position of the eyes, whether the deviation is latent or manifest, intermittent or constant, concomitant or otherwise and according to the age of onset and the relevance of any associated refractive error.