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Psychotic Disorder Due to a General Medical Condition

MedGen UID:
452720
•Concept ID:
C0748076
•
Mental or Behavioral Dysfunction

Definition

A psychotic disorder characterized by prominent hallucinations or delusions that have been determined to be etiologically linked to a general medical condition. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPsychotic Disorder Due to a General Medical Condition

Professional guidelines

PubMed

Pre-treatment, baseline, and outcome differences between early-onset and adult-onset psychosis in an epidemiological cohort of 636 first-episode patients.
Schimmelmann BG, Conus P, Cotton S, McGorry PD, Lambert M
Schizophr Res 2007 Sep;95(1-3):1-8. Epub 2007 Jul 12 doi: 10.1016/j.schres.2007.06.004. PMID: 17628441
Diagnostic stability 18 months after treatment initiation for first-episode psychosis.
Schimmelmann BG, Conus P, Edwards J, McGorry PD, Lambert M
J Clin Psychiatry 2005 Oct;66(10):1239-46. doi: 10.4088/jcp.v66n1006. PMID: 16259537

Recent clinical studies

Etiology

Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E
BMJ 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. PMID: 37648266Free PMC Article
Cognitive behavioural therapy (group) for schizophrenia.
Guaiana G, Abbatecola M, Aali G, Tarantino F, Ebuenyi ID, Lucarini V, Li W, Zhang C, Pinto A
Cochrane Database Syst Rev 2022 Jul 12;7(7):CD009608. doi: 10.1002/14651858.CD009608.pub2. PMID: 35866377Free PMC Article
Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies.
Solmi M, Radua J, Olivola M, Croce E, Soardo L, Salazar de Pablo G, Il Shin J, Kirkbride JB, Jones P, Kim JH, Kim JY, Carvalho AF, Seeman MV, Correll CU, Fusar-Poli P
Mol Psychiatry 2022 Jan;27(1):281-295. Epub 2021 Jun 2 doi: 10.1038/s41380-021-01161-7. PMID: 34079068Free PMC Article
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.
Fusar-Poli P, Salazar de Pablo G, Correll CU, Meyer-Lindenberg A, Millan MJ, Borgwardt S, Galderisi S, Bechdolf A, Pfennig A, Kessing LV, van Amelsvoort T, Nieman DH, Domschke K, Krebs MO, Koutsouleris N, McGuire P, Do KQ, Arango C
JAMA Psychiatry 2020 Jul 1;77(7):755-765. doi: 10.1001/jamapsychiatry.2019.4779. PMID: 32159746
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249

Diagnosis

Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies.
Solmi M, Radua J, Olivola M, Croce E, Soardo L, Salazar de Pablo G, Il Shin J, Kirkbride JB, Jones P, Kim JH, Kim JY, Carvalho AF, Seeman MV, Correll CU, Fusar-Poli P
Mol Psychiatry 2022 Jan;27(1):281-295. Epub 2021 Jun 2 doi: 10.1038/s41380-021-01161-7. PMID: 34079068Free PMC Article
Psychosis.
Julayanont P, Suryadevara U
Continuum (Minneap Minn) 2021 Dec 1;27(6):1682-1711. doi: 10.1212/CON.0000000000001013. PMID: 34881732
Psychosis.
Schrimpf LA, Aggarwal A, Lauriello J
Continuum (Minneap Minn) 2018 Jun;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):845-860. doi: 10.1212/CON.0000000000000602. PMID: 29851881
Catatonia.
Walther S, Strik W
CNS Spectr 2016 Aug;21(4):341-8. Epub 2016 Jun 3 doi: 10.1017/S1092852916000274. PMID: 27255726
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249

Therapy

Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E
BMJ 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. PMID: 37648266Free PMC Article
Cognitive behavioural therapy (group) for schizophrenia.
Guaiana G, Abbatecola M, Aali G, Tarantino F, Ebuenyi ID, Lucarini V, Li W, Zhang C, Pinto A
Cochrane Database Syst Rev 2022 Jul 12;7(7):CD009608. doi: 10.1002/14651858.CD009608.pub2. PMID: 35866377Free PMC Article
Psychosis.
Julayanont P, Suryadevara U
Continuum (Minneap Minn) 2021 Dec 1;27(6):1682-1711. doi: 10.1212/CON.0000000000001013. PMID: 34881732
Catatonia.
Walther S, Strik W
CNS Spectr 2016 Aug;21(4):341-8. Epub 2016 Jun 3 doi: 10.1017/S1092852916000274. PMID: 27255726
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249

Prognosis

The schizophrenia syndrome, circa 2024: What we know and how that informs its nature.
Tandon R, Nasrallah H, Akbarian S, Carpenter WT Jr, DeLisi LE, Gaebel W, Green MF, Gur RE, Heckers S, Kane JM, Malaspina D, Meyer-Lindenberg A, Murray R, Owen M, Smoller JW, Yassin W, Keshavan M
Schizophr Res 2024 Feb;264:1-28. Epub 2023 Dec 12 doi: 10.1016/j.schres.2023.11.015. PMID: 38086109
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.
Fusar-Poli P, Salazar de Pablo G, Correll CU, Meyer-Lindenberg A, Millan MJ, Borgwardt S, Galderisi S, Bechdolf A, Pfennig A, Kessing LV, van Amelsvoort T, Nieman DH, Domschke K, Krebs MO, Koutsouleris N, McGuire P, Do KQ, Arango C
JAMA Psychiatry 2020 Jul 1;77(7):755-765. doi: 10.1001/jamapsychiatry.2019.4779. PMID: 32159746
Effects of Antipsychotic Medication on Brain Structure in Patients With Major Depressive Disorder and Psychotic Features: Neuroimaging Findings in the Context of a Randomized Placebo-Controlled Clinical Trial.
Voineskos AN, Mulsant BH, Dickie EW, Neufeld NH, Rothschild AJ, Whyte EM, Meyers BS, Alexopoulos GS, Hoptman MJ, Lerch JP, Flint AJ
JAMA Psychiatry 2020 Jul 1;77(7):674-683. doi: 10.1001/jamapsychiatry.2020.0036. PMID: 32101271Free PMC Article
Introduction.
Fang Y, Mao R
Adv Exp Med Biol 2019;1180:1-17. doi: 10.1007/978-981-32-9271-0_1. PMID: 31784955
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249

Clinical prediction guides

Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E
BMJ 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. PMID: 37648266Free PMC Article
Physicians' and medical students' beliefs and attitudes toward psychotic disorders: A systematic review.
Le Glaz A, Lemey C, Berrouiguet S, Walter M, Lemogne C, Flahault C
J Psychosom Res 2022 Dec;163:111054. Epub 2022 Oct 13 doi: 10.1016/j.jpsychores.2022.111054. PMID: 36272378
Cognitive behavioural therapy (group) for schizophrenia.
Guaiana G, Abbatecola M, Aali G, Tarantino F, Ebuenyi ID, Lucarini V, Li W, Zhang C, Pinto A
Cochrane Database Syst Rev 2022 Jul 12;7(7):CD009608. doi: 10.1002/14651858.CD009608.pub2. PMID: 35866377Free PMC Article
Postural Sway and Clinical Characteristics in Patients with Psychotic Disorders: A Review.
Fujino H, Imura O
Psychiatr Q 2015 Dec;86(4):603-14. doi: 10.1007/s11126-015-9355-5. PMID: 25791471
Using antipsychotic agents in older patients.
Alexopoulos GS, Streim J, Carpenter D, Docherty JP; Expert Consensus Panel for Using Antipsychotic Drugs in Older Patients
J Clin Psychiatry 2004;65 Suppl 2:5-99; discussion 100-102; quiz 103-4. PMID: 14994733

Recent systematic reviews

Physicians' and medical students' beliefs and attitudes toward psychotic disorders: A systematic review.
Le Glaz A, Lemey C, Berrouiguet S, Walter M, Lemogne C, Flahault C
J Psychosom Res 2022 Dec;163:111054. Epub 2022 Oct 13 doi: 10.1016/j.jpsychores.2022.111054. PMID: 36272378
Cognitive behavioural therapy (group) for schizophrenia.
Guaiana G, Abbatecola M, Aali G, Tarantino F, Ebuenyi ID, Lucarini V, Li W, Zhang C, Pinto A
Cochrane Database Syst Rev 2022 Jul 12;7(7):CD009608. doi: 10.1002/14651858.CD009608.pub2. PMID: 35866377Free PMC Article
Suicidal behavior in juvenile bipolar disorder and major depressive disorder patients: Systematic review and meta-analysis.
Serra G, De Crescenzo F, Maisto F, Galante JR, Iannoni ME, Trasolini M, Maglio G, Tondo L, Baldessarini RJ, Vicari S
J Affect Disord 2022 Aug 15;311:572-581. Epub 2022 May 16 doi: 10.1016/j.jad.2022.05.063. PMID: 35588913
Establishing a clinical service to prevent psychosis: What, how and when? Systematic review.
Salazar de Pablo G, Estradé A, Cutroni M, Andlauer O, Fusar-Poli P
Transl Psychiatry 2021 Jan 13;11(1):43. doi: 10.1038/s41398-020-01165-x. PMID: 33441556Free PMC Article
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.
Fusar-Poli P, Salazar de Pablo G, Correll CU, Meyer-Lindenberg A, Millan MJ, Borgwardt S, Galderisi S, Bechdolf A, Pfennig A, Kessing LV, van Amelsvoort T, Nieman DH, Domschke K, Krebs MO, Koutsouleris N, McGuire P, Do KQ, Arango C
JAMA Psychiatry 2020 Jul 1;77(7):755-765. doi: 10.1001/jamapsychiatry.2019.4779. PMID: 32159746

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