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Stage IIIC Cutaneous Melanoma AJCC v7

MedGen UID:
443630
Concept ID:
C2828036
Neoplastic Process
Synonym: Stage IIIC Skin Melanoma AJCC v7

Definition

Stage IIIC includes: (T1-4b, N1b, M0); (T1-4b, N2b, M0); (T1-4b, N2c, M0); (Any T, N3, M0). T1-4b: Ulcerated cutaneous melanoma of any thickness. N1b: Cutaneous melanoma with macrometastasis in one regional lymph node. N2b: Cutaneous melanoma with macrometastases in 2-3 regional lymph nodes. N2c: Cutaneous melanoma with intralymphatic metastases (in transit or satellite metastases) without metastatic nodes. N3: Cutaneous melanoma with 4 or more metastatic nodes, or matted nodes, or in transit met(s)/satellite(s) with metastatic node(s). M0: No detectable evidence of distant metastases. (from AJCC 7th Ed.) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage IIIC Cutaneous Melanoma AJCC v7

Recent clinical studies

Etiology

Slingluff CL, Lewis KD, Andtbacka R, Hyngstrom J, Milhem M, Markovic SN, Bowles T, Hamid O, Hernandez-Aya L, Claveau J, Jang S, Philips P, Holtan SG, Shaheen MF, Curti B, Schmidt W, Butler MO, Paramo J, Lutzky J, Padmanabhan A, Thomas S, Milton D, Pecora A, Sato T, Hsueh E, Badarinath S, Keech J, Kalmadi S, Kumar P, Weber R, Levine E, Berger A, Bar A, Beck JT, Travers JB, Mihalcioiu C, Gastman B, Beitsch P, Rapisuwon S, Glaspy J, McCarron EC, Gupta V, Behl D, Blumenstein B, Peterkin JJ
J Immunother Cancer 2021 Oct;9(10) doi: 10.1136/jitc-2021-003272. PMID: 34599031Free PMC Article

Therapy

Slingluff CL, Lewis KD, Andtbacka R, Hyngstrom J, Milhem M, Markovic SN, Bowles T, Hamid O, Hernandez-Aya L, Claveau J, Jang S, Philips P, Holtan SG, Shaheen MF, Curti B, Schmidt W, Butler MO, Paramo J, Lutzky J, Padmanabhan A, Thomas S, Milton D, Pecora A, Sato T, Hsueh E, Badarinath S, Keech J, Kalmadi S, Kumar P, Weber R, Levine E, Berger A, Bar A, Beck JT, Travers JB, Mihalcioiu C, Gastman B, Beitsch P, Rapisuwon S, Glaspy J, McCarron EC, Gupta V, Behl D, Blumenstein B, Peterkin JJ
J Immunother Cancer 2021 Oct;9(10) doi: 10.1136/jitc-2021-003272. PMID: 34599031Free PMC Article
Afzal MZ, Shirai K
J Immunother 2019 May;42(4):136-141. doi: 10.1097/CJI.0000000000000265. PMID: 30933044

Supplemental Content

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