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Colorectal carcinoma(CRC)

MedGen UID:
3170
Concept ID:
C0009402
Neoplastic Process
Synonyms: Cancer, Colorectal; Cancers, Colorectal; Carcinoma, Colorectal; Carcinomas, Colorectal; Colorectal Cancer; Colorectal Cancers; Colorectal Carcinoma; Colorectal Carcinomas
 
Monarch Initiative: MONDO:0024331
OMIM®: 114500; 172411; 191170; 516000; 516004; 516020; 516030; 516040

Definition

A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Akdeniz N, Kaplan MA, Uncu D, İnanç M, Kaya S, Dane F, Küçüköner M, Demirci A, Bilici M, Durnalı AG, Koral L, Şendur MAN, Erol C, Türkmen E, Ölmez ÖF, Açıkgöz Ö, Laçin Ş, Şahinli H, Urakçı Z, Işıkdoğan A
Int J Colorectal Dis 2021 Jun;36(6):1311-1319. Epub 2021 Feb 14 doi: 10.1007/s00384-021-03888-9. PMID: 33586012
Krishnamurthi SS, Meropol NJ
Semin Oncol 2011 Aug;38(4):481-2. doi: 10.1053/j.seminoncol.2011.05.001. PMID: 21810506
Goddard AF, James MW, McIntyre AS, Scott BB; British Society of Gastroenterology
Gut 2011 Oct;60(10):1309-16. Epub 2011 May 11 doi: 10.1136/gut.2010.228874. PMID: 21561874

Curated

DailyMed Drug Label, Capecitabine, 2021

Recent clinical studies

Etiology

Bergamaschi L, Chiaravalli S, Signoroni S, Di Bartolomeo M, Ferrari A
Expert Opin Pharmacother 2023 Sep-Dec;24(14):1527-1535. Epub 2023 Jun 29 doi: 10.1080/14656566.2023.2230123. PMID: 37358925
Lesko J, Rastović P, Azinović A, Ðurasović S, Bogut A, Zovko J, Pavlović M, Zovko Z
Med Glas (Zenica) 2020 Feb 1;17(1):151-157. doi: 10.17392/1079-20. PMID: 31845566
Niederreiter L, Adolph TE, Tilg H
Dig Liver Dis 2018 Jul;50(7):647-652. Epub 2018 Apr 3 doi: 10.1016/j.dld.2018.03.030. PMID: 29705028
Benedict M, Galvao Neto A, Zhang X
World J Gastroenterol 2015 Dec 7;21(45):12735-41. doi: 10.3748/wjg.v21.i45.12735. PMID: 26668498Free PMC Article
Hatoum HA, Abi Saad GS, Otrock ZK, Barada KA, Shamseddine AI
Int J Clin Oncol 2011 Jun;16(3):203-9. Epub 2010 Nov 11 doi: 10.1007/s10147-010-0140-z. PMID: 21069550

Diagnosis

Beech C, Hechtman JF
Surg Pathol Clin 2021 Sep;14(3):429-441. doi: 10.1016/j.path.2021.05.007. PMID: 34373094
Hissong E, Pittman ME
Crit Rev Clin Lab Sci 2020 Jan;57(1):22-36. Epub 2019 Oct 11 doi: 10.1080/10408363.2019.1670614. PMID: 31603697
Bhalla A, Zulfiqar M, Bluth MH
Clin Lab Med 2018 Jun;38(2):311-342. doi: 10.1016/j.cll.2018.02.008. PMID: 29776633
Benedict M, Galvao Neto A, Zhang X
World J Gastroenterol 2015 Dec 7;21(45):12735-41. doi: 10.3748/wjg.v21.i45.12735. PMID: 26668498Free PMC Article
Alterescu KB
Nurs Clin North Am 1987 Jun;22(2):281-9. PMID: 3646660

Therapy

Garin E, Guiu B, Edeline J, Rolland Y, Palard X
Cardiovasc Intervent Radiol 2022 Nov;45(11):1608-1621. Epub 2022 Aug 18 doi: 10.1007/s00270-022-03215-x. PMID: 35982334
Zhang KL, Zhu WW, Wang SH, Gao C, Pan JJ, Du ZG, Lu L, Jia HL, Dong QZ, Chen JH, Lu M, Qin LX
Theranostics 2021;11(13):6560-6572. Epub 2021 Apr 27 doi: 10.7150/thno.55609. PMID: 33995676Free PMC Article
Mody K, Baldeo C, Bekaii-Saab T
Cancer J 2018 Jul/Aug;24(4):165-170. doi: 10.1097/PPO.0000000000000328. PMID: 30119079
Perren TJ
Ann Oncol 2016 Apr;27 Suppl 1:i53-i57. doi: 10.1093/annonc/mdw087. PMID: 27141073
Dubel GJ, Soares GM
Surg Oncol Clin N Am 2008 Oct;17(4):957-85, xii. doi: 10.1016/j.soc.2008.04.008. PMID: 18722928

Prognosis

Mathey MD, Pennella CL, Zubizarreta P
Arch Argent Pediatr 2021 Oct;119(5):e487-e498. doi: 10.5546/aap.2021.eng.e487. PMID: 34569749
Perren TJ
Ann Oncol 2016 Apr;27 Suppl 1:i53-i57. doi: 10.1093/annonc/mdw087. PMID: 27141073
Benedict M, Galvao Neto A, Zhang X
World J Gastroenterol 2015 Dec 7;21(45):12735-41. doi: 10.3748/wjg.v21.i45.12735. PMID: 26668498Free PMC Article
Abi Saad GS, Hussein M, El-Saghir NS, Termos S, Sharara AI, Shamseddine A
Int J Clin Oncol 2011 Aug;16(4):306-13. Epub 2011 Jan 22 doi: 10.1007/s10147-010-0182-2. PMID: 21258837
Halle M, Schoenberg MH
Dtsch Arztebl Int 2009 Oct;106(44):722-7. Epub 2009 Oct 30 doi: 10.3238/arztebl.2009.0722. PMID: 19997551Free PMC Article

Clinical prediction guides

Benedict M, Galvao Neto A, Zhang X
World J Gastroenterol 2015 Dec 7;21(45):12735-41. doi: 10.3748/wjg.v21.i45.12735. PMID: 26668498Free PMC Article
Bettington ML, Chetty R
Hum Pathol 2015 Jul;46(7):933-8. Epub 2015 Apr 20 doi: 10.1016/j.humpath.2015.04.002. PMID: 26001333
Ritterhouse LL, Barletta JA
Semin Diagn Pathol 2015 Sep;32(5):400-8. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2015.02.010. PMID: 25744437
Lam AK, Chan SS, Leung M
World J Gastroenterol 2014 Jun 14;20(22):6815-20. doi: 10.3748/wjg.v20.i22.6815. PMID: 24944471Free PMC Article
Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pagès F
J Pathol 2014 Jan;232(2):199-209. doi: 10.1002/path.4287. PMID: 24122236Free PMC Article

Recent systematic reviews

Afolabi H, Md Salleh S, Zakaria Z, Seng CE, Mohd Nafil SNB, Abdul Aziz AAB, Wada Y, Irekeola A
Biomed Res Int 2022;2022:5824183. Epub 2022 Jun 23 doi: 10.1155/2022/5824183. PMID: 35782059Free PMC Article
Falz R, Bischoff C, Thieme R, Lässing J, Mehdorn M, Stelzner S, Busse M, Gockel I
J Cancer Res Clin Oncol 2022 Sep;148(9):2187-2213. Epub 2022 Jun 13 doi: 10.1007/s00432-022-04088-w. PMID: 35695931Free PMC Article
Pyo JS, Sohn JH, Kang G
Hum Pathol 2016 Jul;53:91-6. Epub 2016 Mar 19 doi: 10.1016/j.humpath.2016.02.018. PMID: 27001432
Esin E, Yalcin S
Cancer Treat Rev 2016 Jan;42:82-90. Epub 2015 Nov 10 doi: 10.1016/j.ctrv.2015.10.012. PMID: 26608114
da Costa Vieira RA, Tramonte MS, Lopes LF
Int J Colorectal Dis 2015 Aug;30(8):1001-6. Epub 2015 Apr 28 doi: 10.1007/s00384-015-2202-1. PMID: 25916603

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