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Abnormality of urinary uric acid level

MedGen UID:
1813048
•Concept ID:
C5676600
•
Finding
Synonym: Abnormality of urinary uric acid concentration
 
HPO: HP:0012610

Definition

Abnormal amount of urate in the urine. [from HPO]

Professional guidelines

PubMed

The Impact of Dietary Modifications and Medical Management on 24-Hour Urinary Metabolic Profiles and the Status of Renal Stone Disease in Recurrent Stone Formers.
Abu-Ghanem Y, Kleinmann N, Erlich T, Winkler HZ, Zilberman DE
Isr Med Assoc J 2021 Jan;23(1):12-16. PMID: 33443336
SMRT sequencing revealed to be an effective method for ADTKD-MUC1 diagnosis through follow-up analysis of a Chinese family.
Wang GQ, Rui HL, Dong HR, Sun LJ, Yang M, Wang YY, Ye N, Zhao ZR, Liu XJ, Xu XY, Chen YP, Cheng H
Sci Rep 2020 May 25;10(1):8616. doi: 10.1038/s41598-020-65491-2. PMID: 32451462Free PMC Article
Pathophysiology, clinical consequences, and treatment of tumor lysis syndrome.
Davidson MB, Thakkar S, Hix JK, Bhandarkar ND, Wong A, Schreiber MJ
Am J Med 2004 Apr 15;116(8):546-54. doi: 10.1016/j.amjmed.2003.09.045. PMID: 15063817

Recent clinical studies

Etiology

Relationship between psoriasis and urolithiasis.
Oğuz ID, Oğuz U, Usta M, Kulaklı S, Tosun A, Demirelli E, Akşan B, Emecen Ö, Yüzüak E
J Dermatol 2024 Feb;51(2):280-286. Epub 2023 Dec 12 doi: 10.1111/1346-8138.17058. PMID: 38087833
Combined application of DTI and BOLD-MRI in the assessment of renal injury with hyperuricemia.
Cheng ZY, Lin QT, Chen PK, Si-Tu DK, Qian L, Feng YZ, Cai XR
Abdom Radiol (NY) 2021 Apr;46(4):1694-1702. Epub 2020 Oct 19 doi: 10.1007/s00261-020-02804-z. PMID: 33074425
Uric acid and hypertension: a focused review and practical recommendations.
De Becker B, Borghi C, Burnier M, van de Borne P
J Hypertens 2019 May;37(5):878-883. doi: 10.1097/HJH.0000000000001980. PMID: 30620339
The effect of polymorphism of uric acid transporters on uric acid transport.
Wang Z, Cui T, Ci X, Zhao F, Sun Y, Li Y, Liu R, Wu W, Yi X, Liu C
J Nephrol 2019 Apr;32(2):177-187. Epub 2018 Oct 31 doi: 10.1007/s40620-018-0546-7. PMID: 30382560
Pathophysiology of stone formation.
Robertson WG
Urol Int 1986;41(5):329-33. doi: 10.1159/000281232. PMID: 3544437

Diagnosis

Relationship between psoriasis and urolithiasis.
Oğuz ID, Oğuz U, Usta M, Kulaklı S, Tosun A, Demirelli E, Akşan B, Emecen Ö, Yüzüak E
J Dermatol 2024 Feb;51(2):280-286. Epub 2023 Dec 12 doi: 10.1111/1346-8138.17058. PMID: 38087833
Electrolyte Imbalance in Anti-LGI1 Encephalitis: It Is Not All in Your Head.
Gadoth A, Nisnboym M, Alcalay Y, Zubkov A, Schwartz I, Schwartz D, Abboud M, Rubinek T, Yossepowitch O, Weinstein T
Neurol Neuroimmunol Neuroinflamm 2023 Nov;10(6) Epub 2023 Aug 17 doi: 10.1212/NXI.0000000000200155. PMID: 37591767Free PMC Article
Laboratory and metabolic investigations.
Morava E, Oglesbee D
Handb Clin Neurol 2023;194:167-172. doi: 10.1016/B978-0-12-821751-1.00012-9. PMID: 36813311
Uric acid and hypertension: a focused review and practical recommendations.
De Becker B, Borghi C, Burnier M, van de Borne P
J Hypertens 2019 May;37(5):878-883. doi: 10.1097/HJH.0000000000001980. PMID: 30620339
The effect of polymorphism of uric acid transporters on uric acid transport.
Wang Z, Cui T, Ci X, Zhao F, Sun Y, Li Y, Liu R, Wu W, Yi X, Liu C
J Nephrol 2019 Apr;32(2):177-187. Epub 2018 Oct 31 doi: 10.1007/s40620-018-0546-7. PMID: 30382560

Therapy

Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Mehmood A, Althobaiti F, Zhao L, Usman M, Chen X, Alharthi F, Soliman MM, Shah AA, Murtaza MA, Nadeem M, Ranjha MMAN, Wang C
J Food Biochem 2022 Oct;46(10):e14286. Epub 2022 Aug 5 doi: 10.1111/jfbc.14286. PMID: 35929489
Uric acid and hypertension: a focused review and practical recommendations.
De Becker B, Borghi C, Burnier M, van de Borne P
J Hypertens 2019 May;37(5):878-883. doi: 10.1097/HJH.0000000000001980. PMID: 30620339
Pharmacokinetics, pharmacodynamics, and tolerability of verinurad, a selective uric acid reabsorption inhibitor, in healthy adult male subjects.
Shen Z, Gillen M, Miner JN, Bucci G, Wilson DM, Hall JW
Drug Des Devel Ther 2017;11:2077-2086. Epub 2017 Jul 7 doi: 10.2147/DDDT.S140658. PMID: 28744099Free PMC Article
Uric acid and the kidney.
Fathallah-Shaykh SA, Cramer MT
Pediatr Nephrol 2014 Jun;29(6):999-1008. Epub 2013 Jul 4 doi: 10.1007/s00467-013-2549-x. PMID: 23824181
Pathophysiology, clinical consequences, and treatment of tumor lysis syndrome.
Davidson MB, Thakkar S, Hix JK, Bhandarkar ND, Wong A, Schreiber MJ
Am J Med 2004 Apr 15;116(8):546-54. doi: 10.1016/j.amjmed.2003.09.045. PMID: 15063817

Prognosis

Electrolyte Imbalance in Anti-LGI1 Encephalitis: It Is Not All in Your Head.
Gadoth A, Nisnboym M, Alcalay Y, Zubkov A, Schwartz I, Schwartz D, Abboud M, Rubinek T, Yossepowitch O, Weinstein T
Neurol Neuroimmunol Neuroinflamm 2023 Nov;10(6) Epub 2023 Aug 17 doi: 10.1212/NXI.0000000000200155. PMID: 37591767Free PMC Article
Follow up of renal outcomes in children with solitary kidney.
Akyol Onder EN, Yilmaz O, Taneli C, Ertan P
Pediatr Int 2023 Jan;65(1):e15488. doi: 10.1111/ped.15488. PMID: 36705322
Urinary citrate as a marker of renal function in patients with autosomal dominant polycystic kidney disease.
Borrego Utiel FJ, Herrera Contreras I, Merino García E, Camacho Reina MV, Moriana Domínguez C, Ocaña Pérez E
Int Urol Nephrol 2022 Apr;54(4):873-881. Epub 2021 Jul 19 doi: 10.1007/s11255-021-02953-0. PMID: 34279821
Endocan levels in children with renal hypodysplasia.
Cayci FS, Aydin Z, Aygar IS, Avci B, Inozu M, Aksoy OY, Bayrakci US
Clin Nephrol 2021 Jun;95(6):332-337. doi: 10.5414/CN110402. PMID: 33704056
Urinary biomarkers in the early detection and follow-up of tubular injury in childhood urolithiasis.
Taşdemir M, Fuçucuoğlu D, Küçük SH, Erol M, Yiğit Ö, Bilge I
Clin Exp Nephrol 2018 Feb;22(1):133-141. Epub 2017 Jun 26 doi: 10.1007/s10157-017-1436-3. PMID: 28653226

Clinical prediction guides

Laboratory and metabolic investigations.
Morava E, Oglesbee D
Handb Clin Neurol 2023;194:167-172. doi: 10.1016/B978-0-12-821751-1.00012-9. PMID: 36813311
Follow up of renal outcomes in children with solitary kidney.
Akyol Onder EN, Yilmaz O, Taneli C, Ertan P
Pediatr Int 2023 Jan;65(1):e15488. doi: 10.1111/ped.15488. PMID: 36705322
Study of purine derivatives and their relation to renal disorders in patients with psoriasis.
Bazid HAS, Shoeib MA, El-Sayed S, Mostafa MI, Shoeib MM, Eldeen ES
Int J Dermatol 2023 Jan;62(1):73-78. Epub 2022 Jul 6 doi: 10.1111/ijd.16343. PMID: 35792888
Impaired kidney function biomarkers and risk of severe COVID-19: Analysis of population-based cohort data.
Lin Y, Ma B, Yang Y, Chen Y, Huang J, Li W, Yu X, Liang L
Mol Genet Genomic Med 2022 Nov;10(11):e2047. Epub 2022 Sep 20 doi: 10.1002/mgg3.2047. PMID: 36124564Free PMC Article
Hematopoietic Disorders, Renal Impairment and Growth in Mucopolysaccharidosis-Plus Syndrome.
Sofronova V, Iwata R, Moriya T, Loskutova K, Gurinova E, Chernova M, Timofeeva A, Shvedova A, Vasilev F, Novgorodova S, Terawaki S, Moriwaki T, Sukhomyasova A, Maksimova N, Otomo T
Int J Mol Sci 2022 May 23;23(10) doi: 10.3390/ijms23105851. PMID: 35628659Free PMC Article

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