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Digital pitting scar

MedGen UID:
1619479
•Concept ID:
C3854542
•
Disease or Syndrome
HPO: HP:0031293

Definition

Pinhole-sized concave depressions with hyperkeratosis in the skin of a finger or toe. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDigital pitting scar

Recent clinical studies

Etiology

Differences in clinical presentation and incidence of cardiopulmonary involvement in late-onset versus early-onset systemic sclerosis: inception cohort study.
Wangkaew S, Phiriyakrit P, Sawangduan V, Prasertwittayakij N, Euathrongchit J
Int J Rheum Dis 2018 May;21(5):1082-1092. Epub 2018 Apr 19 doi: 10.1111/1756-185X.13307. PMID: 29673120
Prevalence and predictors of hand involvement in Thai patients with systemic sclerosis.
Wangkaew S, Sivasomboon C, Leungwatthananon W, Kasitanon N, Louthrenoo W
Int J Rheum Dis 2018 Jan;21(1):240-248. Epub 2016 Jul 26 doi: 10.1111/1756-185X.12919. PMID: 27456855
Digital ulcers in scleroderma: staging, characteristics and sub-setting through observation of 1614 digital lesions.
Amanzi L, Braschi F, Fiori G, Galluccio F, Miniati I, Guiducci S, Conforti ML, Kaloudi O, Nacci F, Sacu O, Candelieri A, Pignone A, Rasero L, Conforti D, Matucci-Cerinic M
Rheumatology (Oxford) 2010 Jul;49(7):1374-82. Epub 2010 Apr 16 doi: 10.1093/rheumatology/keq097. PMID: 20400463

Diagnosis

Differences in clinical presentation and incidence of cardiopulmonary involvement in late-onset versus early-onset systemic sclerosis: inception cohort study.
Wangkaew S, Phiriyakrit P, Sawangduan V, Prasertwittayakij N, Euathrongchit J
Int J Rheum Dis 2018 May;21(5):1082-1092. Epub 2018 Apr 19 doi: 10.1111/1756-185X.13307. PMID: 29673120
Skin sclerosis as a manifestation of POEMS syndrome.
Hasegawa M, Orito H, Yamamoto K, Matsushita T, Hamaguchi Y, Fujimoto M, Takehara K
J Dermatol 2012 Nov;39(11):922-6. Epub 2012 Jun 23 doi: 10.1111/j.1346-8138.2012.01609.x. PMID: 22724593
Pitting scars in progressive systemic sclerosis.
Maeda M, Matubara K, Hirano H, Watabe H, Ichiki Y, Mori S
Dermatology 1993;187(2):104-8. doi: 10.1159/000247216. PMID: 8358096

Therapy

Digital ulcers in scleroderma: staging, characteristics and sub-setting through observation of 1614 digital lesions.
Amanzi L, Braschi F, Fiori G, Galluccio F, Miniati I, Guiducci S, Conforti ML, Kaloudi O, Nacci F, Sacu O, Candelieri A, Pignone A, Rasero L, Conforti D, Matucci-Cerinic M
Rheumatology (Oxford) 2010 Jul;49(7):1374-82. Epub 2010 Apr 16 doi: 10.1093/rheumatology/keq097. PMID: 20400463

Prognosis

Differences in clinical presentation and incidence of cardiopulmonary involvement in late-onset versus early-onset systemic sclerosis: inception cohort study.
Wangkaew S, Phiriyakrit P, Sawangduan V, Prasertwittayakij N, Euathrongchit J
Int J Rheum Dis 2018 May;21(5):1082-1092. Epub 2018 Apr 19 doi: 10.1111/1756-185X.13307. PMID: 29673120
Prevalence and predictors of hand involvement in Thai patients with systemic sclerosis.
Wangkaew S, Sivasomboon C, Leungwatthananon W, Kasitanon N, Louthrenoo W
Int J Rheum Dis 2018 Jan;21(1):240-248. Epub 2016 Jul 26 doi: 10.1111/1756-185X.12919. PMID: 27456855
Digital ulcers in scleroderma: staging, characteristics and sub-setting through observation of 1614 digital lesions.
Amanzi L, Braschi F, Fiori G, Galluccio F, Miniati I, Guiducci S, Conforti ML, Kaloudi O, Nacci F, Sacu O, Candelieri A, Pignone A, Rasero L, Conforti D, Matucci-Cerinic M
Rheumatology (Oxford) 2010 Jul;49(7):1374-82. Epub 2010 Apr 16 doi: 10.1093/rheumatology/keq097. PMID: 20400463
Pitting scars in progressive systemic sclerosis.
Maeda M, Matubara K, Hirano H, Watabe H, Ichiki Y, Mori S
Dermatology 1993;187(2):104-8. doi: 10.1159/000247216. PMID: 8358096

Clinical prediction guides

Decreased activation of ataxia telangiectasia mutated (ATM) in monocytes from patients with systemic sclerosis.
Sakata K, Yasuoka H, Yoshimoto K, Takeuchi T
Rheumatology (Oxford) 2020 Dec 1;59(12):3961-3970. doi: 10.1093/rheumatology/keaa312. PMID: 32743653
Differences in clinical presentation and incidence of cardiopulmonary involvement in late-onset versus early-onset systemic sclerosis: inception cohort study.
Wangkaew S, Phiriyakrit P, Sawangduan V, Prasertwittayakij N, Euathrongchit J
Int J Rheum Dis 2018 May;21(5):1082-1092. Epub 2018 Apr 19 doi: 10.1111/1756-185X.13307. PMID: 29673120
Prevalence and predictors of hand involvement in Thai patients with systemic sclerosis.
Wangkaew S, Sivasomboon C, Leungwatthananon W, Kasitanon N, Louthrenoo W
Int J Rheum Dis 2018 Jan;21(1):240-248. Epub 2016 Jul 26 doi: 10.1111/1756-185X.12919. PMID: 27456855
Digital ulcers in scleroderma: staging, characteristics and sub-setting through observation of 1614 digital lesions.
Amanzi L, Braschi F, Fiori G, Galluccio F, Miniati I, Guiducci S, Conforti ML, Kaloudi O, Nacci F, Sacu O, Candelieri A, Pignone A, Rasero L, Conforti D, Matucci-Cerinic M
Rheumatology (Oxford) 2010 Jul;49(7):1374-82. Epub 2010 Apr 16 doi: 10.1093/rheumatology/keq097. PMID: 20400463
Pitting scars in progressive systemic sclerosis.
Maeda M, Matubara K, Hirano H, Watabe H, Ichiki Y, Mori S
Dermatology 1993;187(2):104-8. doi: 10.1159/000247216. PMID: 8358096

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