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Anterior cerebral artery infarction

MedGen UID:
148402
•Concept ID:
C0751843
•
Disease or Syndrome
Synonyms: ACA Infarct; ACA Infarction; ACA Infarctions; ACA Infarcts; Anterior Cerebral Artery Infarction; Anterior Cerebral Artery Stroke; Infarct, ACA; Infarction, ACA; Infarction, Anterior Cerebral Artery; Infarction, Anterior Cerebral Artery Circulation; Infarction, Anterior Cerebral Artery Distribution; Infarctions, ACA; Infarcts, ACA; Stroke, Anterior Cerebral Artery
 
Monarch Initiative: MONDO:0006647

Definition

Necrosis occurring in the anterior cerebral artery system, including branches such as Heubner's artery. These arteries supply blood to the medial and superior parts of the cerebral hemisphere, Infarction in the anterior cerebral artery usually results in sensory and motor impairment in the lower body. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnterior cerebral artery infarction

Professional guidelines

PubMed

Thrombectomy versus Medical Management for Isolated Anterior Cerebral Artery Stroke: An International Multicenter Registry Study.
Meyer L, Stracke P, Broocks G, Elsharkawy M, Sporns P, Piechowiak EI, Kaesmacher J, Maegerlein C, Hernandez Petzsche MR, Zimmermann H, Naziri W, Abdullayev N, Kabbasch C, Diamandis E, Thormann M, Maus V, Fischer S, Möhlenbruch M, Weyland CS, Ernst M, Jamous A, Meila D, Miszczuk M, Siebert E, Lowens S, Krause LU, Yeo L, Tan B, Gopinathan A, Arenillas-Lara JF, Navia P, Raz E, Shapiro M, Arnberg F, Zeleňák K, Martínez-Galdámez M, Alexandrou M, Kastrup A, Papanagiotou P, Kemmling A, Dorn F, Psychogios M, Andersson T, Chapot R, Fiehler J, Hanning U; TOPMOST Study Group
Radiology 2023 Apr;307(2):e220229. Epub 2023 Feb 14 doi: 10.1148/radiol.220229. PMID: 36786705
Management of a wake-up stroke.
Huang X, Alakbarzade V, Khandanpour N, Pereira AC
Pract Neurol 2019 Aug;19(4):326-331. Epub 2019 Mar 14 doi: 10.1136/practneurol-2018-002179. PMID: 30872357
Management of the malignant middle cerebral artery syndrome.
Hwang DY, Matouk CC, Sheth KN
Semin Neurol 2013 Nov;33(5):448-55. Epub 2014 Feb 6 doi: 10.1055/s-0033-1364211. PMID: 24504607

Recent clinical studies

Etiology

Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size.
Costalat V, Jovin TG, Albucher JF, Cognard C, Henon H, Nouri N, Gory B, Richard S, Marnat G, Sibon I, Di Maria F, Annan M, Boulouis G, Cardona P, Obadia M, Piotin M, Bourcier R, Guillon B, Godard S, Pasco-Papon A, Eker OF, Cho TH, Turc G, Naggara O, Velasco S, Lamy M, Clarençon F, Alamowitch S, Renu A, Suissa L, Brunel H, Gentric JC, Timsit S, Lamy C, Chivot C, Macian-Montoro F, Mounayer C, Ozkul-Wermester O, Papagiannaki C, Wolff V, Pop R, Ferrier A, Chabert E, Ricolfi F, Béjot Y, Lopez-Cancio E, Vega P, Spelle L, Denier C, Millán M, Arenillas JF, Mazighi M, Houdart E, Del Mar Freijo M, Duhamel A, Sanossian N, Liebeskind DS, Labreuche J, Lapergue B, Arquizan C; LASTE Trial Investigators
N Engl J Med 2024 May 9;390(18):1677-1689. doi: 10.1056/NEJMoa2314063. PMID: 38718358
A clinical study of 288 patients with anterior cerebral artery infarction.
Cho H, Kim T, Kim YD, Na S, Choi YH, Song IU, Chung SW, Koo J, Kwon H, Park JH, Im H
J Neurol 2022 Jun;269(6):2999-3005. Epub 2021 Nov 16 doi: 10.1007/s00415-021-10904-z. PMID: 34783885
Clinical prognosis of isolated anterior cerebral artery territory infarction: a retrospective study.
Park H, Jeong YS, Lee SH, Jang SH, Kwon DH, Hong JH, Sohn SI, Yoo J
BMC Neurol 2021 Apr 21;21(1):171. doi: 10.1186/s12883-021-02194-9. PMID: 33882861Free PMC Article
Anterior cerebral artery infarcts; two years follow-up study.
Hanoglu L , Khanmammadov E , Demirci S , Altin Ü , Kirbas D , Hanoglu T , Yulug B
Ideggyogy Sz 2018 Sep 30;71(9-10):331-336. doi: 10.18071/isz.71.0331. PMID: 30335265
Treatment of complex anterior cerebral artery aneurysms with Pipeline flow diversion: mid-term results.
Dabus G, Grossberg JA, Cawley CM, Dion JE, Puri AS, Wakhloo AK, Gonsales D, Aguilar-Salinas P, Sauvageau E, Linfante I, Hanel RA
J Neurointerv Surg 2017 Feb;9(2):147-151. Epub 2016 Jul 5 doi: 10.1136/neurintsurg-2016-012519. PMID: 27382125

Diagnosis

Differences in Ischemic Anterior and Posterior Circulation Strokes: A Clinico-Radiological and Outcome Analysis.
Zürcher E, Richoz B, Faouzi M, Michel P
J Stroke Cerebrovasc Dis 2019 Mar;28(3):710-718. Epub 2018 Nov 28 doi: 10.1016/j.jstrokecerebrovasdis.2018.11.016. PMID: 30501979
Anterior cerebral artery infarcts; two years follow-up study.
Hanoglu L , Khanmammadov E , Demirci S , Altin Ü , Kirbas D , Hanoglu T , Yulug B
Ideggyogy Sz 2018 Sep 30;71(9-10):331-336. doi: 10.18071/isz.71.0331. PMID: 30335265
Confined anterior cerebral artery infarction manifesting as isolated unilateral axial weakness.
Honig A, Eliahou R, Auriel E
J Neurol Sci 2017 Feb 15;373:18-20. Epub 2016 Nov 25 doi: 10.1016/j.jns.2016.11.061. PMID: 28131184
Sonographic stroke templates.
Govaert P
Semin Fetal Neonatal Med 2009 Oct;14(5):284-98. Epub 2009 Aug 13 doi: 10.1016/j.siny.2009.07.006. PMID: 19682961
Anterior cerebral artery infarction: stroke mechanism and clinical-imaging study in 100 patients.
Kang SY, Kim JS
Neurology 2008 Jun 10;70(24 Pt 2):2386-93. doi: 10.1212/01.wnl.0000314686.94007.d0. PMID: 18541871

Therapy

Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size.
Costalat V, Jovin TG, Albucher JF, Cognard C, Henon H, Nouri N, Gory B, Richard S, Marnat G, Sibon I, Di Maria F, Annan M, Boulouis G, Cardona P, Obadia M, Piotin M, Bourcier R, Guillon B, Godard S, Pasco-Papon A, Eker OF, Cho TH, Turc G, Naggara O, Velasco S, Lamy M, Clarençon F, Alamowitch S, Renu A, Suissa L, Brunel H, Gentric JC, Timsit S, Lamy C, Chivot C, Macian-Montoro F, Mounayer C, Ozkul-Wermester O, Papagiannaki C, Wolff V, Pop R, Ferrier A, Chabert E, Ricolfi F, Béjot Y, Lopez-Cancio E, Vega P, Spelle L, Denier C, Millán M, Arenillas JF, Mazighi M, Houdart E, Del Mar Freijo M, Duhamel A, Sanossian N, Liebeskind DS, Labreuche J, Lapergue B, Arquizan C; LASTE Trial Investigators
N Engl J Med 2024 May 9;390(18):1677-1689. doi: 10.1056/NEJMoa2314063. PMID: 38718358
Cerebral Embolism as a Result of Facial Filler Injections: A Literature Review.
Wang HC, Yu N, Wang X, Dong R, Long X, Feng X, Li J, Wu WTL
Aesthet Surg J 2022 Feb 15;42(3):NP162-NP175. doi: 10.1093/asj/sjab193. PMID: 33856432Free PMC Article
Ocular and cerebral infarction from periocular filler injection.
Ansari ZA, Choi CJ, Rong AJ, Erickson BP, Tse DT
Orbit 2019 Aug;38(4):322-324. Epub 2018 Oct 30 doi: 10.1080/01676830.2018.1537287. PMID: 30376386
Confined anterior cerebral artery infarction manifesting as isolated unilateral axial weakness.
Honig A, Eliahou R, Auriel E
J Neurol Sci 2017 Feb 15;373:18-20. Epub 2016 Nov 25 doi: 10.1016/j.jns.2016.11.061. PMID: 28131184
Mechanical Thrombectomy of Distal Occlusions in the Anterior Cerebral Artery: Recanalization Rates, Periprocedural Complications, and Clinical Outcome.
Pfaff J, Herweh C, Pham M, Schieber S, Ringleb PA, Bendszus M, Möhlenbruch M
AJNR Am J Neuroradiol 2016 Apr;37(4):673-8. Epub 2015 Nov 5 doi: 10.3174/ajnr.A4594. PMID: 26542233Free PMC Article

Prognosis

Clinical prognosis of isolated anterior cerebral artery territory infarction: a retrospective study.
Park H, Jeong YS, Lee SH, Jang SH, Kwon DH, Hong JH, Sohn SI, Yoo J
BMC Neurol 2021 Apr 21;21(1):171. doi: 10.1186/s12883-021-02194-9. PMID: 33882861Free PMC Article
Differences in Ischemic Anterior and Posterior Circulation Strokes: A Clinico-Radiological and Outcome Analysis.
Zürcher E, Richoz B, Faouzi M, Michel P
J Stroke Cerebrovasc Dis 2019 Mar;28(3):710-718. Epub 2018 Nov 28 doi: 10.1016/j.jstrokecerebrovasdis.2018.11.016. PMID: 30501979
Anterior cerebral artery infarcts; two years follow-up study.
Hanoglu L , Khanmammadov E , Demirci S , Altin Ü , Kirbas D , Hanoglu T , Yulug B
Ideggyogy Sz 2018 Sep 30;71(9-10):331-336. doi: 10.18071/isz.71.0331. PMID: 30335265
Confined anterior cerebral artery infarction manifesting as isolated unilateral axial weakness.
Honig A, Eliahou R, Auriel E
J Neurol Sci 2017 Feb 15;373:18-20. Epub 2016 Nov 25 doi: 10.1016/j.jns.2016.11.061. PMID: 28131184
Sonographic stroke templates.
Govaert P
Semin Fetal Neonatal Med 2009 Oct;14(5):284-98. Epub 2009 Aug 13 doi: 10.1016/j.siny.2009.07.006. PMID: 19682961

Clinical prediction guides

Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size.
Costalat V, Jovin TG, Albucher JF, Cognard C, Henon H, Nouri N, Gory B, Richard S, Marnat G, Sibon I, Di Maria F, Annan M, Boulouis G, Cardona P, Obadia M, Piotin M, Bourcier R, Guillon B, Godard S, Pasco-Papon A, Eker OF, Cho TH, Turc G, Naggara O, Velasco S, Lamy M, Clarençon F, Alamowitch S, Renu A, Suissa L, Brunel H, Gentric JC, Timsit S, Lamy C, Chivot C, Macian-Montoro F, Mounayer C, Ozkul-Wermester O, Papagiannaki C, Wolff V, Pop R, Ferrier A, Chabert E, Ricolfi F, Béjot Y, Lopez-Cancio E, Vega P, Spelle L, Denier C, Millán M, Arenillas JF, Mazighi M, Houdart E, Del Mar Freijo M, Duhamel A, Sanossian N, Liebeskind DS, Labreuche J, Lapergue B, Arquizan C; LASTE Trial Investigators
N Engl J Med 2024 May 9;390(18):1677-1689. doi: 10.1056/NEJMoa2314063. PMID: 38718358
Topographic Evolution of Anterior Cerebral Artery Infarction and Its Impact on Motor Impairment.
Thirugnanachandran T, Ma H, Vuong J, Mitchell M, Wong C, Singhal S, Slater LA, Beare R, Srikanth V, Phan TG
Cerebrovasc Dis 2022;51(2):248-258. Epub 2021 Sep 30 doi: 10.1159/000519134. PMID: 34592733
Clinical prognosis of isolated anterior cerebral artery territory infarction: a retrospective study.
Park H, Jeong YS, Lee SH, Jang SH, Kwon DH, Hong JH, Sohn SI, Yoo J
BMC Neurol 2021 Apr 21;21(1):171. doi: 10.1186/s12883-021-02194-9. PMID: 33882861Free PMC Article
Anterior cerebral artery infarcts; two years follow-up study.
Hanoglu L , Khanmammadov E , Demirci S , Altin Ü , Kirbas D , Hanoglu T , Yulug B
Ideggyogy Sz 2018 Sep 30;71(9-10):331-336. doi: 10.18071/isz.71.0331. PMID: 30335265
Sonographic stroke templates.
Govaert P
Semin Fetal Neonatal Med 2009 Oct;14(5):284-98. Epub 2009 Aug 13 doi: 10.1016/j.siny.2009.07.006. PMID: 19682961

Recent systematic reviews

Systematic review of outcome after ischemic stroke due to anterior circulation occlusion treated with intravenous, intra-arterial, or combined intravenous+intra-arterial thrombolysis.
Mullen MT, Pisapia JM, Tilwa S, Messé SR, Stein SC
Stroke 2012 Sep;43(9):2350-5. Epub 2012 Jul 17 doi: 10.1161/STROKEAHA.111.639211. PMID: 22811451

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