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Sawtooth acanthosis

MedGen UID:
1370360
•Concept ID:
C4476599
•
Anatomical Abnormality
Synonym: Sawtoothed acanthosis
 
HPO: HP:0025122

Definition

A type of epidermal acanthosis characterized by a jagged (sawtooth) appearance of the rete ridges of the epidermis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSawtooth acanthosis

Recent clinical studies

Etiology

Histopathological evaluation of nail lichen planus: A cross-sectional study.
Kharghoria G, Grover C, Bhattacharya SN, Sharma S
J Cutan Pathol 2021 Jan;48(1):11-17. Epub 2020 Sep 22 doi: 10.1111/cup.13783. PMID: 32578239
Lichen planoporitis: keratosis lichenoides chronica revisited.
Kossard S, Lee S
J Cutan Pathol 1998 Apr;25(4):222-7. doi: 10.1111/j.1600-0560.1998.tb01723.x. PMID: 9609142

Diagnosis

Histopathological evaluation of nail lichen planus: A cross-sectional study.
Kharghoria G, Grover C, Bhattacharya SN, Sharma S
J Cutan Pathol 2021 Jan;48(1):11-17. Epub 2020 Sep 22 doi: 10.1111/cup.13783. PMID: 32578239
Linear lichen planus.
Batra P, Wang N, Kamino H, Possick P
Dermatol Online J 2008 Oct 15;14(10):16. PMID: 19061615
Colocalization of lichen planus and vitiligo associated with selective IgA deficiency.
Gül U, Soylu S, Demiriz M
Skinmed 2007 Jul-Aug;6(4):202-3. doi: 10.1111/j.1540-9740.2007.06386.x. PMID: 17618176
Benign lichenoid keratosis.
Frigy AF, Cooper PH
Am J Clin Pathol 1985 Apr;83(4):439-43. doi: 10.1093/ajcp/83.4.439. PMID: 3984937

Therapy

Lichenoid Dermatologic Toxicity From Immune Checkpoint Blockade Therapy: A Detailed Examination of the Clinicopathologic Features.
Tetzlaff MT, Nagarajan P, Chon S, Huen A, Diab A, Omar P, Aung PP, Torres-Cabala CA, Mays SR, Prieto VG, Curry JL
Am J Dermatopathol 2017 Feb;39(2):121-129. doi: 10.1097/DAD.0000000000000688. PMID: 28134729

Clinical prediction guides

Colocalization of lichen planus and vitiligo associated with selective IgA deficiency.
Gül U, Soylu S, Demiriz M
Skinmed 2007 Jul-Aug;6(4):202-3. doi: 10.1111/j.1540-9740.2007.06386.x. PMID: 17618176
Benign lichenoid keratosis.
Frigy AF, Cooper PH
Am J Clin Pathol 1985 Apr;83(4):439-43. doi: 10.1093/ajcp/83.4.439. PMID: 3984937

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