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Rete ridge flattening

MedGen UID:
1369126
•Concept ID:
C4476597
•
Anatomical Abnormality
Synonyms: Flattened rete pegs; Flattened rete ridges
 
HPO: HP:0025117

Definition

Rete pegs (or ridges) are the epithelial extensions that project into the underlying connective tissue in both skin and mucous membranes. Rete ridge flattening refers to the loss of these projections so that the skin epithelium acquires a relatively flat appearance. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRete ridge flattening

Professional guidelines

PubMed

Can we predict postinflammatory hyperpigmentation after laser treatment based on dermoscopic findings of solar lentigo?
Park JH, Lee JH, Chung BY, Kim JE, Shin JH, Oh SH, Choi M, Lee SH, Kim YC, Ryu HJ
Lasers Med Sci 2023 May 29;38(1):130. doi: 10.1007/s10103-023-03790-6. PMID: 37247095
Melanoma in situ versus melanocytic hyperplasia in sun-damaged skin. Assessment of the significance of histopathologic criteria for differential diagnosis.
Weyers W, Bonczkowitz M, Weyers I, Bittinger A, Schill WB
Am J Dermatopathol 1996 Dec;18(6):560-6. doi: 10.1097/00000372-199612000-00002. PMID: 8989926

Recent clinical studies

Etiology

Can we predict postinflammatory hyperpigmentation after laser treatment based on dermoscopic findings of solar lentigo?
Park JH, Lee JH, Chung BY, Kim JE, Shin JH, Oh SH, Choi M, Lee SH, Kim YC, Ryu HJ
Lasers Med Sci 2023 May 29;38(1):130. doi: 10.1007/s10103-023-03790-6. PMID: 37247095
Cryosurgery as a Single Agent and in Combination with Intralesional Corticosteroids Is Effective on Young, Small Keloids and Induces Characteristic Histological and Immunohistological Changes: A Prospective Randomized Trial.
Zouboulis CC, Zouridaki E
Dermatology 2021;237(3):396-406. Epub 2020 Dec 4 doi: 10.1159/000511624. PMID: 33279888
Characteristics of keratinocytes in facial solar lentigo with flattened rete ridges: comparison with melasma.
Shin J, Park JY, Kim SJ, Kang HY
Clin Exp Dermatol 2015 Jul;40(5):489-94. Epub 2015 Feb 22 doi: 10.1111/ced.12621. PMID: 25704166
Two patterns of solar lentigines: a histopathological analysis of 40 Japanese women.
Yonei N, Kaminaka C, Kimura A, Furukawa F, Yamamoto Y
J Dermatol 2012 Oct;39(10):829-32. Epub 2012 May 9 doi: 10.1111/j.1346-8138.2012.01574.x. PMID: 22568408
Comprehensive understanding of idiopathic guttate hypomelanosis: clinical and histopathological correlation.
Kim SK, Kim EH, Kang HY, Lee ES, Sohn S, Kim YC
Int J Dermatol 2010 Feb;49(2):162-6. doi: 10.1111/j.1365-4632.2009.04209.x. PMID: 20465639

Diagnosis

Can we predict postinflammatory hyperpigmentation after laser treatment based on dermoscopic findings of solar lentigo?
Park JH, Lee JH, Chung BY, Kim JE, Shin JH, Oh SH, Choi M, Lee SH, Kim YC, Ryu HJ
Lasers Med Sci 2023 May 29;38(1):130. doi: 10.1007/s10103-023-03790-6. PMID: 37247095
Increased epidermal thickness and abnormal epidermal differentiation in keloid scars.
Limandjaja GC, van den Broek LJ, Waaijman T, van Veen HA, Everts V, Monstrey S, Scheper RJ, Niessen FB, Gibbs S
Br J Dermatol 2017 Jan;176(1):116-126. Epub 2016 Nov 26 doi: 10.1111/bjd.14844. PMID: 27377288
Regression in cutaneous melanoma: a comprehensive review from diagnosis to prognosis.
Ribero S, Moscarella E, Ferrara G, Piana S, Argenziano G, Longo C
J Eur Acad Dermatol Venereol 2016 Dec;30(12):2030-2037. Epub 2016 Jul 12 doi: 10.1111/jdv.13815. PMID: 27401335
Late-onset Rothmund-Thomson syndrome.
Kumar P, Sharma PK, Gautam RK, Jain RK, Kar HK
Int J Dermatol 2007 May;46(5):492-3. doi: 10.1111/j.1365-4632.2007.03248.x. PMID: 17472679
Mucinous nevus.
Yokogawa M, Kamakura T, Ishiguro H, Ikeda M, Kodama H
J Dermatol 2005 Jan;32(1):30-3. doi: 10.1111/j.1346-8138.2005.tb00710.x. PMID: 15841658

Therapy

Cryosurgery as a Single Agent and in Combination with Intralesional Corticosteroids Is Effective on Young, Small Keloids and Induces Characteristic Histological and Immunohistological Changes: A Prospective Randomized Trial.
Zouboulis CC, Zouridaki E
Dermatology 2021;237(3):396-406. Epub 2020 Dec 4 doi: 10.1159/000511624. PMID: 33279888
Reflectance confocal microscopy and histological features of depigmentation after local corticosteroid injection.
Gu AK, Zhang XJ, Liu XP, Kong XJ, Zhang LT
Skin Res Technol 2019 Nov;25(6):835-838. Epub 2019 Jun 18 doi: 10.1111/srt.12730. PMID: 31215072
Histoid leprosy: case report.
Bakry OA, Attia AM
Acta Dermatovenerol Croat 2012;20(4):256-9. PMID: 23317487
Dermatofibroma on the palmar surface of the hand.
Gencoglan G, Karaarslan IK, Dereli T, Kazandi AC
Skinmed 2008 Jan-Feb;7(1):41-3. doi: 10.1111/j.1540-9740.2007.06500.x. PMID: 18174803
Histopathology of solar lentigines of the face: a quantitative study.
Andersen WK, Labadie RR, Bhawan J
J Am Acad Dermatol 1997 Mar;36(3 Pt 1):444-7. doi: 10.1016/s0190-9622(97)80224-1. PMID: 9091478

Prognosis

Can we predict postinflammatory hyperpigmentation after laser treatment based on dermoscopic findings of solar lentigo?
Park JH, Lee JH, Chung BY, Kim JE, Shin JH, Oh SH, Choi M, Lee SH, Kim YC, Ryu HJ
Lasers Med Sci 2023 May 29;38(1):130. doi: 10.1007/s10103-023-03790-6. PMID: 37247095
Regression in cutaneous melanoma: a comprehensive review from diagnosis to prognosis.
Ribero S, Moscarella E, Ferrara G, Piana S, Argenziano G, Longo C
J Eur Acad Dermatol Venereol 2016 Dec;30(12):2030-2037. Epub 2016 Jul 12 doi: 10.1111/jdv.13815. PMID: 27401335
Comprehensive understanding of idiopathic guttate hypomelanosis: clinical and histopathological correlation.
Kim SK, Kim EH, Kang HY, Lee ES, Sohn S, Kim YC
Int J Dermatol 2010 Feb;49(2):162-6. doi: 10.1111/j.1365-4632.2009.04209.x. PMID: 20465639
Restrictive dermopathy: a case report and a critical review of all hypotheses of its origin.
Nijsten TE, De Moor A, Colpaert CG, Robert K, Mahieu LM, Lambert J
Pediatr Dermatol 2002 Jan-Feb;19(1):67-72. doi: 10.1046/j.1525-1470.2002.00029.x. PMID: 11860576

Clinical prediction guides

Can we predict postinflammatory hyperpigmentation after laser treatment based on dermoscopic findings of solar lentigo?
Park JH, Lee JH, Chung BY, Kim JE, Shin JH, Oh SH, Choi M, Lee SH, Kim YC, Ryu HJ
Lasers Med Sci 2023 May 29;38(1):130. doi: 10.1007/s10103-023-03790-6. PMID: 37247095
Increased epidermal thickness and abnormal epidermal differentiation in keloid scars.
Limandjaja GC, van den Broek LJ, Waaijman T, van Veen HA, Everts V, Monstrey S, Scheper RJ, Niessen FB, Gibbs S
Br J Dermatol 2017 Jan;176(1):116-126. Epub 2016 Nov 26 doi: 10.1111/bjd.14844. PMID: 27377288
Regression in cutaneous melanoma: a comprehensive review from diagnosis to prognosis.
Ribero S, Moscarella E, Ferrara G, Piana S, Argenziano G, Longo C
J Eur Acad Dermatol Venereol 2016 Dec;30(12):2030-2037. Epub 2016 Jul 12 doi: 10.1111/jdv.13815. PMID: 27401335
Late-onset Rothmund-Thomson syndrome.
Kumar P, Sharma PK, Gautam RK, Jain RK, Kar HK
Int J Dermatol 2007 May;46(5):492-3. doi: 10.1111/j.1365-4632.2007.03248.x. PMID: 17472679
Mucinous nevus.
Yokogawa M, Kamakura T, Ishiguro H, Ikeda M, Kodama H
J Dermatol 2005 Jan;32(1):30-3. doi: 10.1111/j.1346-8138.2005.tb00710.x. PMID: 15841658

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