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Epidermal inclusion cyst

MedGen UID:
120443
Concept ID:
C0259770
Anatomical Abnormality
Synonym: Horn cysts
SNOMED CT: Epithelial inclusion cyst (419366003); Epidermal inclusion cyst (418930003); EIC - Epidermal inclusion cyst (419893006); Epidermal inclusion cyst (419893006); Inclusion cyst (419893006); Inclusion cyst (419366003)

Definition

The most common type of cutaneous cyst. It results from the proliferation of epidermal cells in a circumscribed space within the dermis. It is usually asymptomatic and presents as a firm, round nodule. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpidermal inclusion cyst

Professional guidelines

PubMed

Handa U, Chhabra S, Mohan H
Diagn Cytopathol 2008 Dec;36(12):861-3. doi: 10.1002/dc.20923. PMID: 18855902
Omole F, Simmons BJ, Hacker Y
Am Fam Physician 2003 Jul 1;68(1):135-40. PMID: 12887119
Penna C, Fallani MG, Fambrini M, Zipoli E, Marchionni M
Am J Obstet Gynecol 2002 Dec;187(6):1550-4. doi: 10.1067/mob.2002.127597. PMID: 12501062

Recent clinical studies

Etiology

Guirguis MS, Arribas EM, Kapoor MM, Patel MM, Perez F, Nia ES, Ding Q, Moseley TW, Adrada BE
Radiographics 2024 Apr;44(4):e230113. doi: 10.1148/rg.230113. PMID: 38483829
Kim SJ, Kim WG
Am J Case Rep 2019 Apr 24;20:580-586. doi: 10.12659/AJCR.914412. PMID: 31015391Free PMC Article
Richardson MP, Foster JR, Logan DB
Foot Ankle Spec 2017 Oct;10(5):470-472. Epub 2017 Feb 6 doi: 10.1177/1938640017690859. PMID: 28161986
Asante A, Omurtag K, Roberts C
Fertil Steril 2010 Aug;94(3):1097.e1-3. Epub 2010 Mar 16 doi: 10.1016/j.fertnstert.2010.02.007. PMID: 20236635
Lucarelli MJ, Ahn HB, Kulkarni AD, Kahana A
Ophthalmic Plast Reconstr Surg 2008 Sep-Oct;24(5):357-9. doi: 10.1097/IOP.0b013e31818324b0. PMID: 18806654

Diagnosis

Zhao A, Kedarisetty S, Arriola AGP, Isaacson G
Ear Nose Throat J 2024 Mar;103(3):183-189. Epub 2021 Sep 22 doi: 10.1177/01455613211044778. PMID: 34549614
Ticknor IL, Cassarino DS
Am J Dermatopathol 2023 Dec 1;45(12):822-824. doi: 10.1097/DAD.0000000000002572. PMID: 37883954
Vazquez Salas S, Pedro K, Balram A, Syed S, Kotaka K, Kadivar A, Eke BO, McFarland M, Sung M, Behera N, Dubner BG, Maleki Z
Acta Cytol 2022;66(5):359-370. Epub 2022 Jun 17 doi: 10.1159/000525144. PMID: 35717936
Bashaireh KM, Audat ZA, Jahmani RA, Aleshawi AJ, Al Sbihi AF
Eur J Orthop Surg Traumatol 2019 Aug;29(6):1355-1358. Epub 2019 Apr 9 doi: 10.1007/s00590-019-02432-4. PMID: 30968204
Hood AF, Lumadue J
Dermatol Clin 1992 Apr;10(2):371-85. PMID: 1318812

Therapy

Vella JB, Wackym PA, Wang H, Roychowdhury ST
Laryngoscope 2021 Mar;131(3):E882-E884. Epub 2020 Aug 8 doi: 10.1002/lary.28941. PMID: 32770806
Baek SO, Shin J, Lee JY
J Craniofac Surg 2020 Jul-Aug;31(5):e493-e494. doi: 10.1097/SCS.0000000000006556. PMID: 32487826
Lekic N, Rosenberg AE, Askari M
J Hand Surg Am 2018 May;43(5):491.e1-491.e4. Epub 2017 Oct 12 doi: 10.1016/j.jhsa.2017.09.008. PMID: 29032284
Saini P, Mansoor MN, Jalali S, Sharma A
Indian J Pediatr 2010 Jul;77(7):815-6. Epub 2010 Jun 29 doi: 10.1007/s12098-010-0106-1. PMID: 20589475
Asante A, Omurtag K, Roberts C
Fertil Steril 2010 Aug;94(3):1097.e1-3. Epub 2010 Mar 16 doi: 10.1016/j.fertnstert.2010.02.007. PMID: 20236635

Prognosis

McLaughlin LA, Yildirim O, Rosenblum MK, Imber BS, Haseltine JM, Zelefsky MJ, Schöder H, Morris MJ, Rafelson WM, Krebs S, Moss NS
J Neurooncol 2023 Jun;163(2):455-462. Epub 2023 May 29 doi: 10.1007/s11060-023-04355-x. PMID: 37247180Free PMC Article
Collins K, Nagarajan P, Aung PP
J Cutan Pathol 2021 Jul;48(7):902-907. Epub 2020 Dec 14 doi: 10.1111/cup.13927. PMID: 33258154
Richardson MP, Foster JR, Logan DB
Foot Ankle Spec 2017 Oct;10(5):470-472. Epub 2017 Feb 6 doi: 10.1177/1938640017690859. PMID: 28161986
Hwang DY, Yim YM, Kwon H, Jung SN
J Craniofac Surg 2008 Nov;19(6):1683-6. doi: 10.1097/SCS.0b013e31818971d1. PMID: 19098581
Sullivan DP, Liberatore LA, April MM, Sassoon J, Ward RF
Ann Otol Rhinol Laryngol 2001 Apr;110(4):340-4. doi: 10.1177/000348940111000409. PMID: 11307910

Clinical prediction guides

Şahin Ö, Varlı EN, Moallim AO, Tolunay HE
Pan Afr Med J 2023;46:23. Epub 2023 Sep 14 doi: 10.11604/pamj.2023.46.23.31939. PMID: 38107336Free PMC Article
Chen R, Krueger S, Flahive J, Mahmoud BH
Dermatol Surg 2023 Oct 1;49(10):921-925. Epub 2023 Jul 28 doi: 10.1097/DSS.0000000000003889. PMID: 37506091
Baek SO, Kim SW, Jung SN, Sohn WI, Kwon H
J Craniofac Surg 2011 May;22(3):1149-51. doi: 10.1097/SCS.0b013e318210bb0e. PMID: 21586975
Hwang DY, Yim YM, Kwon H, Jung SN
J Craniofac Surg 2008 Nov;19(6):1683-6. doi: 10.1097/SCS.0b013e31818971d1. PMID: 19098581
Andreadis AA, Samson MC, Szomstein S, Newman MI
Plast Surg Nurs 2007 Oct-Dec;27(4):202-5. doi: 10.1097/01.PSN.0000306186.72942.ae. PMID: 18165728

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