MN1 MN1 proto-oncogene, transcriptional regulator
Gene ID: 4330, updated on 7-Apr-2024Gene type: protein coding
Also known as: MGCR; MGCR1; CEBALID; MGCR1-PEN; dJ353E16.2
- See all available tests in GTR for this gene
- Go to complete Gene record for MN1
- Go to Variation Viewer for MN1 variants
Summary
Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. GeneReviews: Not available | |
| CEBALID syndrome | See labs |
| Electronic medical records and genomics (eMERGE) network exploration in cataract: Several new potential susceptibility loci. GeneReviews: Not available | |
| Familial meningioma | See labs |
| Gene-Smoking Interactions Identify Several Novel Blood Pressure Loci in the Framingham Heart Study. GeneReviews: Not available |
Genomic context
- Location:
- 22q12.1
- Sequence:
- Chromosome: 22; NC_000022.11 (27748277..27801756, complement)
- Total number of exons:
- 2
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for MN1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- MN1 database
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.