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GTR Home > Conditions/Phenotypes > Premature ovarian failure 16

Premature ovarian failure 16

Summary

Premature ovarian failure-16 (POF16) is characterized by onset of amenorrhea early in the fourth decade of life, accompanied by elevated follicle-stimulating hormone (FSH; see 136530) levels and low estradiol levels. Ovaries are smaller than normal and show a solid echo pattern with no antral follicle (Zhang et al., 2018). [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: BNC, BSN1, HsT19447, POF16, bn1, BNC1
    Summary: basonuclin zinc finger protein 1

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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