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    HLA-DQB1-AS1 HLA-DQB1 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 106480429, updated on 8-Nov-2023

    Summary

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    Official Symbol
    HLA-DQB1-AS1provided by HGNC
    Official Full Name
    HLA-DQB1 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:39762
    See related
    Ensembl:ENSG00000223534 AllianceGenome:HGNC:39762
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in lung (RPKM 47.9), lymph node (RPKM 47.0) and 20 other tissues See more
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    Genomic context

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    Location:
    6p21.32
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (32659880..32660729)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (32482905..32483753)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (32627657..32628506)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene major histocompatibility complex, class II, DR beta 1 Neighboring gene HLA-DQA1 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24360 Neighboring gene major histocompatibility complex, class II, DQ alpha 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:32623606-32624294 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:32632197-32632724 Neighboring gene major histocompatibility complex, class II, DQ beta 1 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 6:32682862 Neighboring gene MT-CO3 pseudogene 1 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 6:32685380 Neighboring gene uncharacterized LOC102725019

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NUDT3 and KLF5 were found to associate with lean mass and HLA-DQB1-AS1 for hand grip strength as candidate genes to target for these phenotypes in sarcopenia. The associated regulatory SNPs are rs464553, rs1028883 and rs3129753 respectively.
      Title: Disentangling the genetics of sarcopenia: prioritization of NUDT3 and KLF5 as genes for lean mass & HLA-DQB1-AS1 for hand grip strength with the associated enhancing SNPs & a scoring system.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    Genotypes

    General gene information

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    Other Names

    • HLA-DQB1 antisense RNA 1 (non-protein coding)
    • XXbac-BPG254F23.5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_133907.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL662789
      Related
      ENST00000419852.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      32659880..32660729
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_3

    Genomic

    1. NT_167245.2 Reference GRCh38.p14 ALT_REF_LOCI_3

      Range
      3900709..3901557
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_5

    Genomic

    1. NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5

      Range
      3956247..3957095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      32482905..32483753
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases