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    Tmco5b transmembrane and coiled-coil domains 5B [ Mus musculus (house mouse) ]

    Gene ID: 75275, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Tmco5bprovided by MGI
    Official Full Name
    transmembrane and coiled-coil domains 5Bprovided by MGI
    Primary source
    MGI:MGI:1922525
    See related
    Ensembl:ENSMUSG00000041255 AllianceGenome:MGI:1922525
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930563P21Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMCO5B (transmembrane and coiled-coil domains 5B (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 7.5) See more
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    Genomic context

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    See Tmco5b in Genome Data Viewer
    Location:
    2 E4; 2 57.3 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (113115440..113127535)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (113285095..113297190)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 22676 Neighboring gene cholinergic receptor, muscarinic 5 Neighboring gene STARR-positive B cell enhancer mm9_chr2:112443695-112443995 Neighboring gene apoptosis, caspase activation inhibitor Neighboring gene STARR-seq mESC enhancer starr_05389 Neighboring gene STARR-seq mESC enhancer starr_05390 Neighboring gene ryanodine receptor 3 Neighboring gene STARR-seq mESC enhancer starr_05392 Neighboring gene STARR-seq mESC enhancer starr_05393 Neighboring gene STARR-seq mESC enhancer starr_05394 Neighboring gene STARR-seq mESC enhancer starr_05395 Neighboring gene predicted gene, 26505 Neighboring gene STARR-seq mESC enhancer starr_05396 Neighboring gene STARR-seq mESC enhancer starr_05397 Neighboring gene STARR-seq mESC enhancer starr_05399 Neighboring gene formin 1 Neighboring gene STARR-seq mESC enhancer starr_05401 Neighboring gene RIKEN cDNA 4930533B01 gene Neighboring gene predicted gene, 54142

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region. Pavel E, et al. Int J Dev Biol, 2007. PMID 17554679
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane and coiled-coil domain-containing protein 5B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029232.2 → NP_083508.1  transmembrane and coiled-coil domain-containing protein 5B

      See identical proteins and their annotated locations for NP_083508.1

      Status: VALIDATED

      Source sequence(s)
      BC050803
      Consensus CDS
      CCDS16558.1
      UniProtKB/Swiss-Prot
      Q80X59, Q9D4S7
      Related
      ENSMUSP00000042247.3, ENSMUST00000040856.3
      Conserved Domains (1) summary
      pfam14992
      Location:30 → 306
      TMCO5; TMCO5 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      113115440..113127535
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500326.1 → XP_006500389.1  transmembrane and coiled-coil domain-containing protein 5B isoform X1

      Conserved Domains (1) summary
      pfam14992
      Location:35 → 311
      TMCO5; TMCO5 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80X59.1 GenPept UniProtKB/Swiss-Prot:Q80X59

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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