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    Tmem140 transmembrane protein 140 [ Mus musculus (house mouse) ]

    Gene ID: 68487, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Tmem140provided by MGI
    Official Full Name
    transmembrane protein 140provided by MGI
    Primary source
    MGI:MGI:1915737
    See related
    Ensembl:ENSMUSG00000057137 AllianceGenome:MGI:1915737
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110007F12Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMEM140 (transmembrane protein 140). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in lung adult (RPKM 26.9), subcutaneous fat pad adult (RPKM 16.7) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmem140 in Genome Data Viewer
    Location:
    6 B1; 6 15.18 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (34840081..34851881)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (34863146..34874946)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ATP/GTP binding protein-like 3 Neighboring gene ribosomal protein L7A pseudogene Neighboring gene predicted gene, 46957 Neighboring gene cell cycle regulator of NHEJ Neighboring gene WD repeat domain 91 Neighboring gene STARR-positive B cell enhancer mm9_chr6:34860831-34861132 Neighboring gene stimulated by retinoic acid gene 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 140

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368365.1 → NP_001355294.1  transmembrane protein 140

      Status: VALIDATED

      Source sequence(s)
      AC153869
      Consensus CDS
      CCDS19996.1
      UniProtKB/Swiss-Prot
      Q8BGY5, Q8VDY2
      Conserved Domains (1) summary
      pfam14985
      Location:6 → 185
      TM140; TM140 protein family

    2. NM_197986.3 → NP_932103.1  transmembrane protein 140

      See identical proteins and their annotated locations for NP_932103.1

      Status: VALIDATED

      Source sequence(s)
      AC153869
      Consensus CDS
      CCDS19996.1
      UniProtKB/Swiss-Prot
      Q8BGY5, Q8VDY2
      Related
      ENSMUSP00000074482.4, ENSMUST00000074949.4
      Conserved Domains (1) summary
      pfam14985
      Location:6 → 185
      TM140; TM140 protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      34840081..34851881
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506541.3 → XP_006506604.1  transmembrane protein 140 isoform X1

      See identical proteins and their annotated locations for XP_006506604.1

      UniProtKB/Swiss-Prot
      Q8BGY5, Q8VDY2
      Conserved Domains (1) summary
      pfam14985
      Location:6 → 185
      TM140; TM140 protein family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BGY5.1 GenPept UniProtKB/Swiss-Prot:Q8BGY5

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