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    LOC100136153 beta2-adrenergic receptor [ Oncorhynchus mykiss (rainbow trout) ]

    Gene ID: 100136153, updated on 14-Dec-2023

    Summary

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    Gene symbol
    LOC100136153
    Gene description
    beta2-adrenergic receptor
    See related
    Ensembl:ENSOMYG00000017194
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oncorhynchus mykiss
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
    Also known as
    adrb2
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    Genomic context

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    See LOC100136153 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    101 current USDA_OmykA_1.1 (GCF_013265735.2) 12 NC_048576.1 (55047160..55052488)
    100 previous assembly Omyk_1.0 (GCF_002163495.1) 12 NC_035088.1 (51463644..51471715)

    Chromosome 12 - NC_048576.1Genomic Context describing neighboring genes Neighboring gene interleukin 12B, b Neighboring gene ubiquitin domain containing 2 Neighboring gene actin-binding LIM protein 3 Neighboring gene actin filament-associated protein 1-like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A putative beta2-adrenoceptor from the rainbow trout (Oncorhynuchus mykiss). Molecular characterization and pharmacology. Nickerson JG, et al. Eur J Biochem, 2001 Dec. PMID 11737201

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables beta2-adrenergic receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables norepinephrine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of smooth muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-2 adrenergic receptor
    Names
    beta-2 adrenoceptor
    beta-2 adrenoreceptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001124440.1 → NP_001117912.1  beta-2 adrenergic receptor

      See identical proteins and their annotated locations for NP_001117912.1

      Status: PROVISIONAL

      Source sequence(s)
      AY044093
      UniProtKB/Swiss-Prot
      Q8UUY8
      UniProtKB/TrEMBL
      A0A060XC03
      Related
      ENSOMYP00000036931.2, ENSOMYT00000040321.2
      Conserved Domains (2) summary
      pfam00001
      Location:53 → 334
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:51 → 149
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Oncorhynchus mykiss Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USDA_OmykA_1.1 Primary Assembly

    Genomic

    1. NC_048576.1 Reference USDA_OmykA_1.1 Primary Assembly

      Range
      55047160..55052488
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036936676.1 → XP_036792571.1  beta-2 adrenergic receptor isoform X1

      UniProtKB/TrEMBL
      A0A060XC03, A0A8C7QJ79
      Conserved Domains (2) summary
      cd14964
      Location:38 → 64
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:37 → 344
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_021622407.2 → XP_021478082.2  beta-2 adrenergic receptor isoform X1

      UniProtKB/TrEMBL
      A0A060XC03, A0A8C7QJ79
      Conserved Domains (2) summary
      cd14964
      Location:38 → 64
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:37 → 344
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8UUY8.1 GenPept UniProtKB/Swiss-Prot:Q8UUY8

    Gene LinkOut

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