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    MINK1 misshapen like kinase 1 [ Homo sapiens (human) ]

    Gene ID: 50488, updated on 11-Apr-2024

    Summary

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    Official Symbol
    MINK1provided by HGNC
    Official Full Name
    misshapen like kinase 1provided by HGNC
    Primary source
    HGNC:HGNC:17565
    See related
    Ensembl:ENSG00000141503 MIM:609426; AllianceGenome:HGNC:17565
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    B55; ZC3; MINK; YSK2; MAP4K6; MEKKK 6
    Summary
    This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016]
    Expression
    Ubiquitous expression in skin (RPKM 48.7), brain (RPKM 31.3) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    17p13.2
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (4833340..4898061)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (4722898..4788313)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (4736635..4801356)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8045 Neighboring gene chromosome 17 open reading frame 114 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr17:4711183-4712382 Neighboring gene phospholipase D2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:4735692-4736478 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8046 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8047 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:4752245-4752960 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:4752961-4753674 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:4757141-4758092 Neighboring gene Sharpr-MPRA regulatory region 481 Neighboring gene ATPase H+ transporting V0 subunit c pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8048 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11550 Neighboring gene RNA, 7SL, cytoplasmic 784, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8049 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8050 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11551 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:4805105-4805746 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:4805747-4806388 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11552 Neighboring gene Sharpr-MPRA regulatory region 10924 Neighboring gene chromosome 17 open reading frame 107 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:4811144-4811970 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:4811971-4812796 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:4812797-4813623 Neighboring gene cholinergic receptor nicotinic epsilon subunit Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11554 Neighboring gene glycoprotein Ib platelet subunit alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Multi-Omic Investigations of a 17-19 Translocation Links MINK1 Disruption to Autism, Epilepsy and Osteoporosis. Eisfeldt J, et al. Int J Mol Sci, 2022 Aug 20. PMID 36012658, Free PMC Article
    2. The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins. Daulat AM, et al. J Cell Sci, 2022 Sep 1. PMID 35971817
    3. The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71. Leong SY, et al. PLoS Pathog, 2015 Mar. PMID 25747578, Free PMC Article
    4. Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis. Hyodo T, et al. J Biol Chem, 2012 Jul 20. PMID 22665485, Free PMC Article
    5. Mutational study of the nuclear factor kappa B inducing kinase gene in patients with progressive supranuclear palsy. Campdelacreu J, et al. Neurosci Lett, 2003 Apr 10. PMID 12668260

    See all (70) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins.
      Title: The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins.
    2. Multi-Omic Investigations of a 17-19 Translocation Links MINK1 Disruption to Autism, Epilepsy and Osteoporosis.
      Title: Multi-Omic Investigations of a 17-19 Translocation Links MINK1 Disruption to Autism, Epilepsy and Osteoporosis.
    3. LncRNA SNHG14 contributes to proinflammatory cytokine production in rheumatoid arthritis via the regulation of the miR-17-5p/MINK1-JNK pathway.
      Title: LncRNA SNHG14 contributes to proinflammatory cytokine production in rheumatoid arthritis via the regulation of the miR-17-5p/MINK1-JNK pathway.
    4. Results find MINK1 interacting with full-length and truncated APC. Its is negatively regulated by APC independently of b-catenin. MINK1 localizes to cell-cell junctions and enhances cell adhesion and proliferation.
      Title: Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics.
    5. MINK plays a functional role in the IRES-mediated translation of EV71 viral RNA and may provide a potential target for the development of specific antiviral strategies against EV71 infection
      Title: The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71.
    6. Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis.
      Title: Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis.
    7. MINK1 interacts with and phosphorylates PRICKLE1 and PRICKLE2.
      Title: Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation.
    8. MINK interaction with Rap2 plays a critical role in maintaining the morphological integrity of dendrites and synaptic transmission.
      Title: MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function.
    9. Observational study of gene-disease association. (HuGE Navigator)
      Title: Molecular genetic analysis of long QT syndrome in Norway indicating a high prevalence of heterozygous mutation carriers.
    10. Analysis of the coding region of the NIK gene in progressive supranuclear palsy (PSP) patients through single strand conformation polymorphism and direct sequencing does not support a pathogenic role of the NIK gene in PSP.
      Title: Mutational study of the nuclear factor kappa B inducing kinase gene in patients with progressive supranuclear palsy.
    Submit: New GeneRIF Correction See all GeneRIFs (11)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC21111

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in JNK cascade TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in brain development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in chemical synaptic transmission ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in dendrite morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    NOT involved_in microvillus assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuron projection morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of JNK cascade IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of JNK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of p38MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of AMPA receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cell migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell-matrix adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular exosome HDA PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    misshapen-like kinase 1
    Names
    GCK family kinase MINK
    MAPK/ERK kinase kinase kinase 6
    MEK kinase kinase 6
    misshapen/NIK-related kinase
    mitogen-activated protein kinase kinase kinase kinase 6
    NP_001020108.1
    NP_001308165.1
    NP_056531.1
    NP_722549.2
    NP_733763.1
    XP_006721594.1
    XP_006721595.1
    XP_006721599.1
    XP_011522208.1
    XP_016880193.1
    XP_016880194.1
    XP_016880195.1
    XP_016880196.1
    XP_016880197.1
    XP_047292121.1
    XP_047292122.1
    XP_047292123.1
    XP_047292124.1
    XP_047292125.1
    XP_047292126.1
    XP_047292127.1
    XP_047292128.1
    XP_047292129.1
    XP_047292130.1
    XP_047292131.1
    XP_047292132.1
    XP_047292133.1
    XP_047292134.1
    XP_047292135.1
    XP_054172280.1
    XP_054172281.1
    XP_054172282.1
    XP_054172283.1
    XP_054172284.1
    XP_054172285.1
    XP_054172286.1
    XP_054172287.1
    XP_054172288.1
    XP_054172289.1
    XP_054172290.1
    XP_054172291.1
    XP_054172292.1
    XP_054172293.1
    XP_054172294.1
    XP_054172295.1
    XP_054172296.1
    XP_054172297.1
    XP_054172298.1
    XP_054172299.1
    XP_054172300.1
    XP_054172301.1
    XP_054172302.1
    XP_054172303.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_028005.1 RefSeqGene

      Range
      5001..69722
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001024937.4 → NP_001020108.1  misshapen-like kinase 1 isoform 4

      See identical proteins and their annotated locations for NP_001020108.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon and contains another alternate in-frame exon compared to variant 1. The resulting isoform (4) has the same N- and C-termini and is longer compared to isoform 1.
      Source sequence(s)
      AB041926, AL157418, AY775058, DA653105
      Consensus CDS
      CCDS45590.1
      UniProtKB/Swiss-Prot
      Q8N4C8
      Related
      ENSP00000406487.3, ENST00000453408.7
      Conserved Domains (3) summary
      smart00036
      Location:994 → 1292
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:25 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06636
      Location:8 → 289
      STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

    2. NM_001321236.2 → NP_001308165.1  misshapen-like kinase 1 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AB041926, AL157418, BC094686, DA653105
      UniProtKB/Swiss-Prot
      Q8N4C8
      Conserved Domains (3) summary
      smart00036
      Location:922 → 1220
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:11 → 234
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:1 → 234
      PKc_like; Protein Kinases, catalytic domain

    3. NM_015716.5 → NP_056531.1  misshapen-like kinase 1 isoform 1

      See identical proteins and their annotated locations for NP_056531.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest isoform (1).
      Source sequence(s)
      AB035698, AB041926, AL157418, DA653105
      UniProtKB/Swiss-Prot
      Q8N4C8
      Conserved Domains (3) summary
      smart00036
      Location:977 → 1275
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:25 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06636
      Location:8 → 289
      STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

    4. NM_153827.5 → NP_722549.2  misshapen-like kinase 1 isoform 3

      See identical proteins and their annotated locations for NP_722549.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) includes an additional in-frame exon, compared to variant 1, resulting in the longest isoform (3) which has a unique internal segment, compared to isoform 1.
      Source sequence(s)
      AB035698, AB041926, AL157418, BC034673, DA653105
      Consensus CDS
      CCDS45588.1
      UniProtKB/Swiss-Prot
      D3DTK3, D3DTK4, Q5U8Z0, Q8N4C8, Q9P1X1, Q9P2R8
      Related
      ENSP00000347427.6, ENST00000355280.11
      Conserved Domains (3) summary
      smart00036
      Location:1014 → 1312
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:25 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06636
      Location:8 → 289
      STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

    5. NM_170663.5 → NP_733763.1  misshapen-like kinase 1 isoform 2

      See identical proteins and their annotated locations for NP_733763.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) includes an additional in-frame exon, compared to variant 1, resulting in a longer isoform (2) that has a unique internal segment, compared to isoform 1.
      Source sequence(s)
      AB041926, AL157418, DA653105
      Consensus CDS
      CCDS45589.1
      UniProtKB/Swiss-Prot
      Q8N4C8
      Related
      ENSP00000269296.7, ENST00000347992.11
      Conserved Domains (3) summary
      smart00036
      Location:985 → 1283
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:25 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06636
      Location:8 → 289
      STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      4833340..4898061
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006721531.2 → XP_006721594.1  misshapen-like kinase 1 isoform X1

      Conserved Domains (3) summary
      smart00036
      Location:1043 → 1341
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:25 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06636
      Location:8 → 289
      STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

    2. XM_006721532.2 → XP_006721595.1  misshapen-like kinase 1 isoform X2

      Conserved Domains (3) summary
      smart00036
      Location:1042 → 1340
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:25 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06636
      Location:8 → 289
      STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

    3. XM_006721536.2 → XP_006721599.1  misshapen-like kinase 1 isoform X11

      Conserved Domains (3) summary
      smart00036
      Location:1006 → 1304
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:25 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06636
      Location:8 → 289
      STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

    4. XM_017024706.1 → XP_016880195.1  misshapen-like kinase 1 isoform X12

    5. XM_017024705.1 → XP_016880194.1  misshapen-like kinase 1 isoform X5

    6. XM_047436166.1 → XP_047292122.1  misshapen-like kinase 1 isoform X6

    7. XM_047436168.1 → XP_047292124.1  misshapen-like kinase 1 isoform X8

    8. XM_047436173.1 → XP_047292129.1  misshapen-like kinase 1 isoform X17

    9. XM_047436170.1 → XP_047292126.1  misshapen-like kinase 1 isoform X13

    10. XM_047436176.1 → XP_047292132.1  misshapen-like kinase 1 isoform X21

    11. XM_047436177.1 → XP_047292133.1  misshapen-like kinase 1 isoform X22

    12. XM_017024704.1 → XP_016880193.1  misshapen-like kinase 1 isoform X3

    13. XM_047436165.1 → XP_047292121.1  misshapen-like kinase 1 isoform X4

    14. XM_047436167.1 → XP_047292123.1  misshapen-like kinase 1 isoform X7

    15. XM_011523906.1 → XP_011522208.1  misshapen-like kinase 1 isoform X9

      Conserved Domains (3) summary
      smart00036
      Location:1011 → 1309
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00220
      Location:25 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06636
      Location:8 → 289
      STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

    16. XM_047436169.1 → XP_047292125.1  misshapen-like kinase 1 isoform X10

    17. XM_047436174.1 → XP_047292130.1  misshapen-like kinase 1 isoform X18

    18. XM_047436175.1 → XP_047292131.1  misshapen-like kinase 1 isoform X19

    19. XM_047436171.1 → XP_047292127.1  misshapen-like kinase 1 isoform X14

    20. XM_047436172.1 → XP_047292128.1  misshapen-like kinase 1 isoform X15

    21. XM_047436178.1 → XP_047292134.1  misshapen-like kinase 1 isoform X23

      Related
      ENST00000572330.5

    22. XM_047436179.1 → XP_047292135.1  misshapen-like kinase 1 isoform X24

    23. XM_017024708.2 → XP_016880197.1  misshapen-like kinase 1 isoform X20

    24. XM_017024707.3 → XP_016880196.1  misshapen-like kinase 1 isoform X16

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      4722898..4788313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054316305.1 → XP_054172280.1  misshapen-like kinase 1 isoform X1

    2. XM_054316306.1 → XP_054172281.1  misshapen-like kinase 1 isoform X2

    3. XM_054316315.1 → XP_054172290.1  misshapen-like kinase 1 isoform X11

    4. XM_054316316.1 → XP_054172291.1  misshapen-like kinase 1 isoform X12

    5. XM_054316309.1 → XP_054172284.1  misshapen-like kinase 1 isoform X5

    6. XM_054316310.1 → XP_054172285.1  misshapen-like kinase 1 isoform X6

    7. XM_054316312.1 → XP_054172287.1  misshapen-like kinase 1 isoform X8

    8. XM_054316321.1 → XP_054172296.1  misshapen-like kinase 1 isoform X17

    9. XM_054316317.1 → XP_054172292.1  misshapen-like kinase 1 isoform X13

    10. XM_054316325.1 → XP_054172300.1  misshapen-like kinase 1 isoform X21

    11. XM_054316326.1 → XP_054172301.1  misshapen-like kinase 1 isoform X22

    12. XM_054316307.1 → XP_054172282.1  misshapen-like kinase 1 isoform X3

    13. XM_054316308.1 → XP_054172283.1  misshapen-like kinase 1 isoform X4

    14. XM_054316311.1 → XP_054172286.1  misshapen-like kinase 1 isoform X7

    15. XM_054316313.1 → XP_054172288.1  misshapen-like kinase 1 isoform X9

    16. XM_054316314.1 → XP_054172289.1  misshapen-like kinase 1 isoform X10

    17. XM_054316322.1 → XP_054172297.1  misshapen-like kinase 1 isoform X18

    18. XM_054316323.1 → XP_054172298.1  misshapen-like kinase 1 isoform X19

    19. XM_054316318.1 → XP_054172293.1  misshapen-like kinase 1 isoform X14

    20. XM_054316319.1 → XP_054172294.1  misshapen-like kinase 1 isoform X15

    21. XM_054316327.1 → XP_054172302.1  misshapen-like kinase 1 isoform X23

    22. XM_054316328.1 → XP_054172303.1  misshapen-like kinase 1 isoform X24

    23. XM_054316320.1 → XP_054172295.1  misshapen-like kinase 1 isoform X16

    24. XM_054316324.1 → XP_054172299.1  misshapen-like kinase 1 isoform X20

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8N4C8.2 GenPept UniProtKB/Swiss-Prot:Q8N4C8

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