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    Mup19 major urinary protein 19 [ Mus musculus (house mouse) ]

    Gene ID: 100189605, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Mup19provided by MGI
    Official Full Name
    major urinary protein 19provided by MGI
    Primary source
    MGI:MGI:3705235
    See related
    Ensembl:ENSMUSG00000078673 AllianceGenome:MGI:3705235
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mup6; Mup8; Mup11; Mup14; Mup17; Gm12552; 100039247
    Summary
    Is expressed in liver. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward liver adult (RPKM 2730.8) See more
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    Genomic context

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    See Mup19 in Genome Data Viewer
    Location:
    4 B3; 4 32.9 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (61696561..61700597, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (61778324..61782355, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene major urinary protein, pseudogene 15 Neighboring gene major urinary protein 18 Neighboring gene major urinary protein, pseudogene 16 Neighboring gene STARR-seq mESC enhancer starr_10399 Neighboring gene major urinary protein 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Analysis of mouse major urinary protein genes: variation between the exonic sequences of group 1 genes and a comparison with an active gene out with group 1 both suggest that gene conversion has occurred between MUP genes. Clark AJ, et al. EMBO J, 1985 Dec 1. PMID 3004936, Free PMC Article
    2. Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver. Jiang J, et al. J Biol Chem, 2017 Apr 21. PMID 28258223, Free PMC Article
    3. Species specificity in major urinary proteins by parallel evolution. Logan DW, et al. PLoS One, 2008 Sep 25. PMID 18815613, Free PMC Article
    4. Identification of protein pheromones that promote aggressive behaviour. Chamero P, et al. Nature, 2007 Dec 6. PMID 18064011
    5. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Charkoftaki G, et al. Hum Genomics, 2019 Feb 19. PMID 30782214, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    major urinary protein 11
    Names
    Alpha-2U-globulin
    Group 1, BS6
    MUP 6
    MUP11 and MUP8
    Major urinary protein 6
    Major urinary proteins 11 and 8
    major urinary protein 14
    major urinary protein 17

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135127.2 → NP_001128599.1  major urinary protein 11 precursor

      See identical proteins and their annotated locations for NP_001128599.1

      Status: VALIDATED

      Source sequence(s)
      AK013259
      Consensus CDS
      CCDS51200.1
      UniProtKB/Swiss-Prot
      P02762, P11589, P70119, Q78EF5, Q91V46, Q99JF6
      UniProtKB/TrEMBL
      A2CGB6, B5TE76
      Related
      ENSMUSP00000079442.3, ENSMUST00000080606.9
      Conserved Domains (1) summary
      cd19428
      Location:23 → 180
      lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      61696561..61700597 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537526.5 → XP_006537589.1  major urinary protein 11 isoform X1

      See identical proteins and their annotated locations for XP_006537589.1

      UniProtKB/TrEMBL
      A9C496
      Conserved Domains (1) summary
      cd19428
      Location:23 → 172
      lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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