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    LINC00987 long intergenic non-protein coding RNA 987 [ Homo sapiens (human) ]

    Gene ID: 100499405, updated on 10-Oct-2023

    Summary

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    Official Symbol
    LINC00987provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 987provided by HGNC
    Primary source
    HGNC:HGNC:48911
    See related
    Ensembl:ENSG00000237248 AllianceGenome:HGNC:48911
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in gall bladder (RPKM 3.1), spleen (RPKM 2.8) and 25 other tissues See more
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    Genomic context

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    Location:
    12p13.31
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (9240073..9262901)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (9222589..9245418)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (9392669..9415497)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene alpha-2-macroglobulin pseudogene 1 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr12:9393003-9394202 Neighboring gene microRNA 1244-3 Neighboring gene pregnancy zone protein-like Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4223 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4224 Neighboring gene prothymosin alpha pseudogene 4 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:9435851-9436699 Neighboring gene DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11-like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:9442077-9442928 Neighboring gene uncharacterized LOC105369649

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LINC00987 Ameliorates COPD by Regulating LPS-Induced Cell Apoptosis, Oxidative Stress, Inflammation and Autophagy Through Let-7b-5p/SIRT1 Axis. Wang Y, et al. Int J Chron Obstruct Pulmon Dis, 2020. PMID 33311978, Free PMC Article
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC00987 Ameliorates COPD by Regulating LPS-Induced Cell Apoptosis, Oxidative Stress, Inflammation and Autophagy Through Let-7b-5p/SIRT1 Axis.
      Title: LINC00987 Ameliorates COPD by Regulating LPS-Induced Cell Apoptosis, Oxidative Stress, Inflammation and Autophagy Through Let-7b-5p/SIRT1 Axis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Clone Names

    • FLJ44260

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_036466.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175
      Related
      ENST00000427111.4

    2. NR_137429.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175

    3. NR_137430.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175

    4. NR_137431.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175

    5. NR_137432.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175

    6. NR_137433.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175

    7. NR_137434.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175

    8. NR_137435.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175

    9. NR_137436.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010175

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      9240073..9262901
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      9222589..9245418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Chemical Information
    Molecular Biology Databases