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    Lrrc74a leucine rich repeat containing 74A [ Mus musculus (house mouse) ]

    Gene ID: 627607, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Lrrc74aprovided by MGI
    Official Full Name
    leucine rich repeat containing 74Aprovided by MGI
    Primary source
    MGI:MGI:3646959
    See related
    Ensembl:ENSMUSG00000059114 AllianceGenome:MGI:3646959
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm6772; Lrrc74; EG627607
    Summary
    Orthologous to human LRRC74A (leucine rich repeat containing 74A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 21.3) See more
    Orthologs
    human all
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    Genomic context

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    See Lrrc74a in Genome Data Viewer
    Location:
    12 D2; 12 40.9 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (86781119..86815799)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (86734345..86769025)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene angel homolog 1 Neighboring gene pyruvate kinase, muscle pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E5342 Neighboring gene predicted gene, 32755 Neighboring gene STARR-positive B cell enhancer ABC_E5343 Neighboring gene STARR-positive B cell enhancer ABC_E1448 Neighboring gene STARR-seq mESC enhancer starr_32839 Neighboring gene STARR-positive B cell enhancer ABC_E10768 Neighboring gene predicted gene, 53733 Neighboring gene STARR-seq mESC enhancer starr_32843 Neighboring gene STARR-positive B cell enhancer ABC_E2392 Neighboring gene VISTA enhancer mm1444 Neighboring gene predicted gene, 32806 Neighboring gene predicted gene, 51955

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 74A
    Names
    leucine rich repeat containing 74

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195767.2 → NP_001182696.1  leucine-rich repeat-containing protein 74A

      See identical proteins and their annotated locations for NP_001182696.1

      Status: VALIDATED

      Source sequence(s)
      AC102689
      Consensus CDS
      CCDS56848.1
      UniProtKB/TrEMBL
      A0A1Y7VMD6, F6QBN8
      Related
      ENSMUSP00000093183.6, ENSMUST00000095527.6
      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:73 → 333
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. NM_001418263.1 → NP_001405192.1  leucine-rich repeat-containing protein 74A

      Status: VALIDATED

      Source sequence(s)
      AC102689
      UniProtKB/TrEMBL
      F6QBN8
      Related
      ENSMUSP00000152661.2, ENSMUST00000223308.2

    RNA

    1. NR_184703.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC102689

    2. NR_184704.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC102689

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      86781119..86815799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246837.2 → XP_030102697.1  leucine-rich repeat-containing protein 74A isoform X2

      UniProtKB/TrEMBL
      A0A1Y7VMD6
      Conserved Domains (2) summary
      sd00033
      Location:110 → 138
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:70 → 295
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. XM_006516126.3 → XP_006516189.1  leucine-rich repeat-containing protein 74A isoform X1

      See identical proteins and their annotated locations for XP_006516189.1

      UniProtKB/TrEMBL
      A0A1Y7VMD6, F6QBN8
      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:73 → 333
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    3. XM_006516127.4 → XP_006516190.1  leucine-rich repeat-containing protein 74A isoform X1

      See identical proteins and their annotated locations for XP_006516190.1

      UniProtKB/TrEMBL
      A0A1Y7VMD6, F6QBN8
      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:73 → 333
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    4. XM_011244155.4 → XP_011242457.1  leucine-rich repeat-containing protein 74A isoform X1

      See identical proteins and their annotated locations for XP_011242457.1

      UniProtKB/TrEMBL
      A0A1Y7VMD6, F6QBN8
      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:73 → 333
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    5. XM_030246838.1 → XP_030102698.1  leucine-rich repeat-containing protein 74A isoform X3

      Conserved Domains (2) summary
      sd00033
      Location:59 → 87
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:2 → 244
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    6. XM_017315151.2 → XP_017170640.1  leucine-rich repeat-containing protein 74A isoform X2

      UniProtKB/TrEMBL
      A0A1Y7VMD6
      Conserved Domains (2) summary
      sd00033
      Location:110 → 138
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:70 → 295
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    7. XM_006516130.2 → XP_006516193.1  leucine-rich repeat-containing protein 74A isoform X4

      See identical proteins and their annotated locations for XP_006516193.1

      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:73 → 256
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    RNA

    1. XR_003950075.1 RNA Sequence

      Related
      ENSMUST00000222180.2
    Nucleotide Protein Strain
    Heading Accession and Version

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