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    Fibp [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40163, updated on 10-May-2024

    Summary

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    Official Symbol
    Fibpprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036911
    Locus tag
    Dmel_CG8660
    See related
    AllianceGenome:FB:FBgn0036911
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8660; Dmel\CG8660; DrFIBP; F1bp
    Summary
    Predicted to enable fibroblast growth factor binding activity. Predicted to be active in nucleus. Is expressed in organism and spermatozoon. Orthologous to human FIBP (FGF1 intracellular binding protein). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See Fibp in Genome Data Viewer
    Location:
    76D1-76D1; 3-46 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19816085..19817967, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19809185..19811067, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 305a1 Neighboring gene cycle Neighboring gene Deformed epidermal autoregulatory factor-1 Neighboring gene tricornered

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster. Kolpakova E, et al. Gene, 2003 May 22. PMID 12801646
    2. Identification of genes involved in the same pathways using a Hidden Markov Model-based approach. Senf A, et al. Bioinformatics, 2009 Nov 15. PMID 19720676
    3. Drosophila importin alpha1 performs paralog-specific functions essential for gametogenesis. Ratan R, et al. Genetics, 2008 Feb. PMID 18245351, Free PMC Article
    4. Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex. Wen H, et al. Genes Dev, 2008 Mar 1. PMID 18316477, Free PMC Article
    5. DEAF-1 function is essential for the early embryonic development of Drosophila. Veraksa A, et al. Genesis, 2002 Jun. PMID 12112874

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    fibp
    Names
    CG8660-PH
    CG8660-PI
    CG8660-PJ
    Fibp-PH
    Fibp-PI
    Fibp-PJ

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19816085..19817967 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275137.1 → NP_001262066.2  fibp, isoform I [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8WR19, Q8WR20
      Conserved Domains (1) summary
      pfam05427
      Location:2 → 357
      FIBP; Acidic fibroblast growth factor binding (FIBP)

    2. NM_206401.2 → NP_996123.3  fibp, isoform H [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8WR19, Q8WR20
      Conserved Domains (1) summary
      pfam05427
      Location:2 → 357
      FIBP; Acidic fibroblast growth factor binding (FIBP)

    3. NM_001275138.1 → NP_001262067.2  fibp, isoform J [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PFY4
      Conserved Domains (1) summary
      pfam05427
      Location:2 → 248
      FIBP; Acidic fibroblast growth factor binding (FIBP)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PFY4 M9PFY4
    Q7K1D3 Q7K1D3
    Q8WR19 Q8WR19
    Q8WR20 Q8WR20
    Q9VW45 Q9VW45

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