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    Celf4 CUGBP, Elav-like family member 4 [ Mus musculus (house mouse) ]

    Gene ID: 108013, updated on 12-May-2024

    Summary

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    Official Symbol
    Celf4provided by MGI
    Official Full Name
    CUGBP, Elav-like family member 4provided by MGI
    Primary source
    MGI:MGI:1932407
    See related
    Ensembl:ENSMUSG00000024268 AllianceGenome:MGI:1932407
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Brul4; Brunol4; BRUNOL-4; A230070D14Rik; C130060B05Rik
    Summary
    Enables mRNA binding activity. Acts upstream of or within several processes, including mRNA splice site selection; negative regulation of excitatory postsynaptic potential; and negative regulation of mRNA splicing, via spliceosome. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; mammary gland; retina; and spleen. Orthologous to human CELF4 (CUGBP Elav-like family member 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in frontal lobe adult (RPKM 30.6), CNS E18 (RPKM 25.8) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Celf4 in Genome Data Viewer
    Location:
    18 A2; 18 13.92 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (25610677..25887577, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (25477620..25754520, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene formin homology 2 domain containing 3 Neighboring gene STARR-seq mESC enhancer starr_44075 Neighboring gene 39S ribosomal protein L42, mitochondrial pseudogene Neighboring gene expressed sequence AW554918 Neighboring gene tubulin polyglutamylase complex subunit 2 Neighboring gene STARR-seq mESC enhancer starr_44077 Neighboring gene STARR-seq mESC enhancer starr_44078 Neighboring gene STARR-seq mESC enhancer starr_44080 Neighboring gene STARR-positive B cell enhancer ABC_E3225 Neighboring gene predicted gene, 32825 Neighboring gene predicted gene 3227 Neighboring gene predicted gene, 32896 Neighboring gene predicted gene, 33228 Neighboring gene predicted gene 7847 Neighboring gene STARR-seq mESC enhancer starr_44087 Neighboring gene STARR-seq mESC enhancer starr_44088 Neighboring gene STARR-seq mESC enhancer starr_44090 Neighboring gene STARR-seq mESC enhancer starr_44091 Neighboring gene STARR-seq mESC enhancer starr_44092 Neighboring gene predicted gene, 23674

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. CELF4 regulates spine formation and depression-like behaviors of mice. Shen Y, et al. Biochem Biophys Res Commun, 2022 May 21. PMID 35306363
    2. CELF4 regulates translation and local abundance of a vast set of mRNAs, including genes associated with regulation of synaptic function. Wagnon JL, et al. PLoS Genet, 2012. PMID 23209433, Free PMC Article
    3. Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. Ladd AN, et al. Mol Cell Biol, 2005 Jul. PMID 15988035, Free PMC Article
    4. Identification and characterization of murine Brunol4, a new member of the elav/bruno family. Meins M, et al. Cytogenet Genome Res, 2002. PMID 12438720
    5. Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice. Sun W, et al. J Physiol, 2013 Jan 1. PMID 23090952, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.
      Title: Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.
    2. CELF4 regulates spine formation and depression-like behaviors of mice.
      Title: CELF4 regulates spine formation and depression-like behaviors of mice.
    3. Celf4 might be regulating alternative early in retinal development.
      Title: The expression analysis of Sfrs10 and Celf4 during mouse retinal development.
    4. we suggest that CELF4 deficiency leads to abnormal neuronal function by combining a specific effect on neuronal excitation with a general impairment of synaptic transmission.
      Title: CELF4 regulates translation and local abundance of a vast set of mRNAs, including genes associated with regulation of synaptic function.
    5. Data point strongly to the conclusion that Celf4 deletion primarily from excitatory neurons promotes convulsive seizure phenotypes.
      Title: Etiology of a genetically complex seizure disorder in Celf4 mutant mice.
    6. Brunol4 deficiency in mice results in a complex seizure phenotype, likely due to the coordinate dysregulation of several molecules, providing a unique new animal model of epilepsy
      Title: Complex seizure disorder caused by Brunol4 deficiency in mice.
    7. CELF protein activity is required for normal alternative splicing in the heart in vivo and normal CELF-mediated alternative splicing regulation is in turn required for normal cardiac function.
      Title: Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy.
    8. cloning and characterization
      Title: Identification and characterization of murine Brunol4, a new member of the elav/bruno family.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pre-mRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of excitatory postsynaptic potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within mRNA splice site recognition IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of excitatory postsynaptic potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of retina development in camera-type eye IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CUGBP Elav-like family member 4
    Names
    CUG-BP- and ETR-3-like factor 4
    RNA-binding protein BRUNOL-4
    bruno-like 4, RNA binding protein
    bruno-like protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001146292.2 → NP_001139764.1  CUGBP Elav-like family member 4 isoform 22

      See identical proteins and their annotated locations for NP_001139764.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform (22, also known as A).
      Source sequence(s)
      AC121094, AF515450, AK038871, AK048427, AK078071, BC048405, CX242398
      Consensus CDS
      CCDS50241.1
      UniProtKB/Swiss-Prot
      Q7TSY6
      Related
      ENSMUSP00000111483.3, ENSMUST00000115816.3
      Conserved Domains (3) summary
      cd12639
      Location:415 → 493
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    2. NM_001146293.2 → NP_001139765.1  CUGBP Elav-like family member 4 isoform 35

      See identical proteins and their annotated locations for NP_001139765.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) encodes isoform (37, also known as B).
      Source sequence(s)
      AC121094, AF515450, AK038871, AK048427, AK078071, BC052744, CX242398
      Consensus CDS
      CCDS89205.1
      UniProtKB/Swiss-Prot
      Q7TSY6
      Related
      ENSMUSP00000153326.2, ENSMUST00000223704.2
      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 474
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. NM_001146294.2 → NP_001139766.1  CUGBP Elav-like family member 4 isoform 29

      See identical proteins and their annotated locations for NP_001139766.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes isoform (29, also known as C).
      Source sequence(s)
      AC121094, AF515450, AK038871, AK048427, AK078071, BE861427, CX242398
      Consensus CDS
      CCDS89206.1
      UniProtKB/Swiss-Prot
      Q7TSY6
      Related
      ENSMUSP00000025117.8, ENSMUST00000025117.14
      Conserved Domains (3) summary
      cd12639
      Location:406 → 484
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    4. NM_001174074.2 → NP_001167545.1  CUGBP Elav-like family member 4 isoform 51

      See identical proteins and their annotated locations for NP_001167545.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) encodes isoform (51, also known as F).
      Source sequence(s)
      AC121094, AC144938, AK051458, BC052744
      Consensus CDS
      CCDS89204.1
      UniProtKB/Swiss-Prot
      Q7TSY6
      Related
      ENSMUSP00000153258.2, ENSMUST00000224553.2
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl25887
      Location:56 → 452
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

    5. NM_001362275.1 → NP_001349204.1  CUGBP Elav-like family member 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 463
      RRM_SF; RNA recognition motif (RRM) superfamily

    6. NM_001362276.1 → NP_001349205.1  CUGBP Elav-like family member 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 444
      RRM_SF; RNA recognition motif (RRM) superfamily

    7. NM_001362277.1 → NP_001349206.1  CUGBP Elav-like family member 4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 443
      RRM_SF; RNA recognition motif (RRM) superfamily

    8. NM_001362278.1 → NP_001349207.1  CUGBP Elav-like family member 4 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:404 → 452
      RRM_SF; RNA recognition motif (RRM) superfamily

    9. NM_001362279.1 → NP_001349208.1  CUGBP Elav-like family member 4 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:417 → 445
      RRM_SF; RNA recognition motif (RRM) superfamily

    10. NM_001362280.1 → NP_001349209.1  CUGBP Elav-like family member 4 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 444
      RRM_SF; RNA recognition motif (RRM) superfamily

    11. NM_001362281.1 → NP_001349210.1  CUGBP Elav-like family member 4 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 444
      RRM_SF; RNA recognition motif (RRM) superfamily

    12. NM_001362282.1 → NP_001349211.1  CUGBP Elav-like family member 4 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 443
      RRM_SF; RNA recognition motif (RRM) superfamily

    13. NM_001362283.1 → NP_001349212.1  CUGBP Elav-like family member 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 443
      RRM_SF; RNA recognition motif (RRM) superfamily

    14. NM_001362284.1 → NP_001349213.1  CUGBP Elav-like family member 4 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:405 → 433
      RRM_SF; RNA recognition motif (RRM) superfamily

    15. NM_001362285.1 → NP_001349214.1  CUGBP Elav-like family member 4 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:414 → 442
      RRM_SF; RNA recognition motif (RRM) superfamily

    16. NM_001362286.1 → NP_001349215.1  CUGBP Elav-like family member 4 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:142 → 222
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:407 → 435
      RRM_SF; RNA recognition motif (RRM) superfamily

    17. NM_001362288.1 → NP_001349217.1  CUGBP Elav-like family member 4 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:406 → 434
      RRM_SF; RNA recognition motif (RRM) superfamily

    18. NM_001362289.1 → NP_001349218.1  CUGBP Elav-like family member 4 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:405 → 433
      RRM_SF; RNA recognition motif (RRM) superfamily

    19. NM_001362290.1 → NP_001349219.1  CUGBP Elav-like family member 4 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:405 → 433
      RRM_SF; RNA recognition motif (RRM) superfamily

    20. NM_001362291.1 → NP_001349220.1  CUGBP Elav-like family member 4 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:404 → 432
      RRM_SF; RNA recognition motif (RRM) superfamily

    21. NM_001362292.1 → NP_001349221.1  CUGBP Elav-like family member 4 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12639
      Location:405 → 501
      RRM3_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    22. NM_001362293.1 → NP_001349222.1  CUGBP Elav-like family member 4 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:378 → 422
      RRM_SF; RNA recognition motif (RRM) superfamily

    23. NM_001362294.1 → NP_001349223.1  CUGBP Elav-like family member 4 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl25887
      Location:56 → 378
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

    24. NM_001362295.1 → NP_001349224.1  CUGBP Elav-like family member 4 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12639
      Location:416 → 494
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    25. NM_001362297.1 → NP_001349226.1  CUGBP Elav-like family member 4 isoform 21

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12639
      Location:416 → 494
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    26. NM_001362299.1 → NP_001349228.1  CUGBP Elav-like family member 4 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12639
      Location:415 → 493
      RRM3_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    27. NM_001362300.1 → NP_001349229.1  CUGBP Elav-like family member 4 isoform 24

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12639
      Location:415 → 493
      RRM3_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    28. NM_001362301.1 → NP_001349230.1  CUGBP Elav-like family member 4 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (4) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 490
      RRM_SF; RNA recognition motif (RRM) superfamily
      cl25887
      Location:56 → 378
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

    29. NM_001362302.1 → NP_001349231.1  CUGBP Elav-like family member 4 isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 226
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12639
      Location:411 → 489
      RRM3_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    30. NM_001362303.1 → NP_001349232.1  CUGBP Elav-like family member 4 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 489
      RRM_SF; RNA recognition motif (RRM) superfamily

    31. NM_001362304.1 → NP_001349233.1  CUGBP Elav-like family member 4 isoform 28

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12639
      Location:406 → 484
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    32. NM_001362308.1 → NP_001349237.1  CUGBP Elav-like family member 4 isoform 30

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12639
      Location:405 → 483
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    33. NM_001362309.1 → NP_001349238.1  CUGBP Elav-like family member 4 isoform 31

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12639
      Location:404 → 482
      RRM3_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    34. NM_001362310.1 → NP_001349239.1  CUGBP Elav-like family member 4 isoform 32

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:405 → 481
      RRM_SF; RNA recognition motif (RRM) superfamily

    35. NM_001362311.1 → NP_001349240.1  CUGBP Elav-like family member 4 isoform 33

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      UniProtKB/Swiss-Prot
      Q7TSY6, Q80Y76, Q811Z7, Q8BKM2, Q8BLM9, Q8BXA2, Q99PE0
      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:417 → 475
      RRM_SF; RNA recognition motif (RRM) superfamily

    36. NM_001362313.1 → NP_001349242.1  CUGBP Elav-like family member 4 isoform 34

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 474
      RRM_SF; RNA recognition motif (RRM) superfamily

    37. NM_001362315.1 → NP_001349244.1  CUGBP Elav-like family member 4 isoform 35

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Consensus CDS
      CCDS89205.1
      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 474
      RRM_SF; RNA recognition motif (RRM) superfamily

    38. NM_001362316.1 → NP_001349245.1  CUGBP Elav-like family member 4 isoform 36

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 474
      RRM_SF; RNA recognition motif (RRM) superfamily

    39. NM_001362322.1 → NP_001349251.1  CUGBP Elav-like family member 4 isoform 39

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 473
      RRM_SF; RNA recognition motif (RRM) superfamily

    40. NM_001362323.1 → NP_001349252.1  CUGBP Elav-like family member 4 isoform 40

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 473
      RRM_SF; RNA recognition motif (RRM) superfamily

    41. NM_001362324.1 → NP_001349253.1  CUGBP Elav-like family member 4 isoform 42

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:414 → 472
      RRM_SF; RNA recognition motif (RRM) superfamily

    42. NM_001362325.1 → NP_001349254.1  CUGBP Elav-like family member 4 isoform 43

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:407 → 465
      RRM_SF; RNA recognition motif (RRM) superfamily

    43. NM_001362326.1 → NP_001349255.1  CUGBP Elav-like family member 4 isoform 44

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:406 → 464
      RRM_SF; RNA recognition motif (RRM) superfamily

    44. NM_001362327.1 → NP_001349256.1  CUGBP Elav-like family member 4 isoform 45

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:406 → 464
      RRM_SF; RNA recognition motif (RRM) superfamily

    45. NM_001362328.1 → NP_001349257.1  CUGBP Elav-like family member 4 isoform 46

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:405 → 463
      RRM_SF; RNA recognition motif (RRM) superfamily

    46. NM_001362329.1 → NP_001349258.1  CUGBP Elav-like family member 4 isoform 47

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:405 → 463
      RRM_SF; RNA recognition motif (RRM) superfamily

    47. NM_001362330.1 → NP_001349259.1  CUGBP Elav-like family member 4 isoform 48

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:404 → 462
      RRM_SF; RNA recognition motif (RRM) superfamily

    48. NM_001362331.1 → NP_001349260.1  CUGBP Elav-like family member 4 isoform 49

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 456
      RRM_SF; RNA recognition motif (RRM) superfamily

    49. NM_001362332.1 → NP_001349261.1  CUGBP Elav-like family member 4 isoform 50

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 455
      RRM_SF; RNA recognition motif (RRM) superfamily

    50. NM_001362334.1 → NP_001349263.1  CUGBP Elav-like family member 4 isoform 52

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:142 → 222
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl25887
      Location:56 → 444
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

    51. NM_001362335.1 → NP_001349264.1  CUGBP Elav-like family member 4 isoform 53

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      TIGR01661
      Location:56 → 443
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    52. NM_001362336.1 → NP_001349265.1  CUGBP Elav-like family member 4 isoform 54

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      TIGR01661
      Location:56 → 442
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    53. NM_001362337.1 → NP_001349266.1  CUGBP Elav-like family member 4 isoform 55

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938
      Conserved Domains (3) summary
      TIGR01628
      Location:30 → 254
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12635
      Location:27 → 107
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:293 → 351
      RRM_SF; RNA recognition motif (RRM) superfamily

    54. NM_133195.4 → NP_573458.2  CUGBP Elav-like family member 4 isoform 38

      See identical proteins and their annotated locations for NP_573458.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) encodes isoform (41, also known as D).
      Source sequence(s)
      AC121094, AF515450, AK038871, AK048427, AK078071, CX242398
      Consensus CDS
      CCDS29106.1
      UniProtKB/Swiss-Prot
      Q7TSY6
      Related
      ENSMUSP00000153226.2, ENSMUST00000225477.2
      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:415 → 473
      RRM_SF; RNA recognition motif (RRM) superfamily

    RNA

    1. NR_155522.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    2. NR_155523.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    3. NR_155524.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    4. NR_155525.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    5. NR_155526.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    6. NR_155527.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    7. NR_155528.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    8. NR_155529.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    9. NR_155530.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    10. NR_155531.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    11. NR_155532.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    12. NR_155533.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC121094, AC144938

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      25610677..25887577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030250270.1 → XP_030106130.1  CUGBP Elav-like family member 4 isoform X8

      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:140 → 220
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:406 → 446
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. XM_030250269.1 → XP_030106129.1  CUGBP Elav-like family member 4 isoform X2

      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:406 → 434
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_006525518.3 → XP_006525581.1  CUGBP Elav-like family member 4 isoform X7

      See identical proteins and their annotated locations for XP_006525581.1

      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:407 → 447
      RRM_SF; RNA recognition motif (RRM) superfamily

    4. XM_030250268.1 → XP_030106128.1  CUGBP Elav-like family member 4 isoform X1

      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:407 → 435
      RRM_SF; RNA recognition motif (RRM) superfamily

    5. XM_006525513.3 → XP_006525576.1  CUGBP Elav-like family member 4 isoform X4

      Conserved Domains (3) summary
      cd12639
      Location:407 → 485
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:141 → 221
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    6. XM_006525517.3 → XP_006525580.1  CUGBP Elav-like family member 4 isoform X6

      See identical proteins and their annotated locations for XP_006525580.1

      Conserved Domains (3) summary
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:150 → 230
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:416 → 456
      RRM_SF; RNA recognition motif (RRM) superfamily

    7. XM_006525515.3 → XP_006525578.1  CUGBP Elav-like family member 4 isoform X5

      See identical proteins and their annotated locations for XP_006525578.1

      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:417 → 457
      RRM_SF; RNA recognition motif (RRM) superfamily

    8. XM_006525511.3 → XP_006525574.1  CUGBP Elav-like family member 4 isoform X3

      Conserved Domains (4) summary
      TIGR01628
      Location:56 → 378
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12639
      Location:417 → 495
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12632
      Location:49 → 135
      RRM1_CELF3_4_5_6; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cd12635
      Location:151 → 231
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    9. XM_036160940.1 → XP_036016833.1  CUGBP Elav-like family member 4 isoform X11

      Conserved Domains (3) summary
      TIGR01628
      Location:21 → 245
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12635
      Location:18 → 98
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:283 → 341
      RRM_SF; RNA recognition motif (RRM) superfamily

    10. XM_036160939.1 → XP_036016832.1  CUGBP Elav-like family member 4 isoform X10

      Conserved Domains (3) summary
      TIGR01628
      Location:26 → 255
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12635
      Location:28 → 108
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      cl17169
      Location:293 → 351
      RRM_SF; RNA recognition motif (RRM) superfamily

    11. XM_036160938.1 → XP_036016831.1  CUGBP Elav-like family member 4 isoform X9

      Conserved Domains (3) summary
      cd12639
      Location:293 → 371
      RRM3_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins
      TIGR01661
      Location:31 → 378
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cd12635
      Location:28 → 108
      RRM2_CELF3_4_5_6; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001146295.1: Suppressed sequence

      Description
      NM_001146295.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7TSY6.2 GenPept UniProtKB/Swiss-Prot:Q7TSY6

    Gene LinkOut

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