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    Ctag2 cancer/testis antigen 2 [ Mus musculus (house mouse) ]

    Gene ID: 70062, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Ctag2provided by MGI
    Official Full Name
    cancer/testis antigen 2provided by MGI
    Primary source
    MGI:MGI:1917312
    See related
    Ensembl:ENSMUSG00000031181 AllianceGenome:MGI:1917312
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700030B21Rik
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine metabolic process. Predicted to be located in centrosome; cytoplasm; and nuclear body. Predicted to be part of EKC/KEOPS complex. Orthologous to human CTAG1A (cancer/testis antigen 1A) and CTAG2 (cancer/testis antigen 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 56.6) See more
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    Genomic context

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    See Ctag2 in Genome Data Viewer
    Location:
    X A7.1; X 34.64 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (64091250..64092623)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (65047644..65049017)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_47271 Neighboring gene STARR-seq mESC enhancer starr_47272 Neighboring gene DDB1 and CUL4 associated factor 13 pseudogene Neighboring gene STARR-seq mESC enhancer starr_47273 Neighboring gene STARR-seq mESC enhancer starr_47274 Neighboring gene STARR-seq mESC enhancer starr_47275 Neighboring gene STARR-seq mESC enhancer starr_47277 Neighboring gene coiled-coil domain containing 75 pseudogene Neighboring gene STARR-seq mESC enhancer starr_47278 Neighboring gene STARR-seq mESC enhancer starr_47279 Neighboring gene STARR-seq mESC enhancer starr_47280 Neighboring gene STARR-seq mESC enhancer starr_47281 Neighboring gene STARR-seq mESC enhancer starr_47282 Neighboring gene STARR-seq mESC enhancer starr_47283 Neighboring gene STARR-seq mESC enhancer starr_47284 Neighboring gene STARR-seq mESC enhancer starr_47285 Neighboring gene STARR-seq mESC enhancer starr_47286 Neighboring gene tetratricopeptide repeat domain 39C pseudogene Neighboring gene H2A histone family member L1R, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Interleukin-2-induced, melanoma-specific T cells recognize CAMEL, an unexpected translation product of LAGE-1. Aarnoudse CA, et al. Int J Cancer, 1999 Jul 30. PMID 10399963
    2. The alternative open reading frame of LAGE-1 gives rise to multiple promiscuous HLA-DR-restricted epitopes recognized by T-helper 1-type tumor-reactive CD4+ T cells. Mandic M, et al. Cancer Res, 2003 Oct 1. PMID 14559844
    3. Multiple pathogenic and benign genomic rearrangements occur at a 35 kb duplication involving the NEMO and LAGE2 genes. Aradhya S, et al. Hum Mol Genet, 2001 Oct 15. PMID 11709543
    4. Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis. Morimoto K, et al. Sci Rep, 2020 Jun 3. PMID 32493902, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in tRNA threonylcarbamoyladenosine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of EKC/KEOPS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cancer/testis antigen 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027302.2 → NP_081578.1  cancer/testis antigen 2

      See identical proteins and their annotated locations for NP_081578.1

      Status: VALIDATED

      Source sequence(s)
      AI503560, AK006526
      Consensus CDS
      CCDS30168.1
      UniProtKB/TrEMBL
      Q9D9S4
      Related
      ENSMUSP00000033524.3, ENSMUST00000033524.3
      Conserved Domains (1) summary
      pfam09341
      Location:131 → 202
      Pcc1; Transcription factor Pcc1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      64091250..64092623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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