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    FAM86C1P family with sequence similarity 86 member C1, pseudogene [ Homo sapiens (human) ]

    Gene ID: 55199, updated on 10-Oct-2023

    Summary

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    Official Symbol
    FAM86C1Pprovided by HGNC
    Official Full Name
    family with sequence similarity 86 member C1, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:25561
    See related
    Ensembl:ENSG00000158483 MIM:616124; AllianceGenome:HGNC:25561
    Gene type
    unknown
    RefSeq status
    MODEL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM86C; FAM86C1
    Summary
    Predicted to enable protein-L-histidine N-tele-methyltransferase activity. Predicted to be involved in peptidyl-histidine methylation, to form tele-methylhistidine. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in thyroid (RPKM 3.4), endometrium (RPKM 1.8) and 25 other tissues See more

    Genomic context

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    See FAM86C1P in Genome Data Viewer
    Location:
    11q13.4
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (71787514..71799661)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (71714420..71726582)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene MPRA-validated peak1333 silencer Neighboring gene small nuclear ribonucleoprotein polypeptide C pseudogene 14 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:71445659-71446532 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 8 Neighboring gene XNDC1N-ZNF705EP-ALG1L9P readthrough Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3711 Neighboring gene ALG1 like 9, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3712 Neighboring gene zinc finger protein 705E, pseudogene Neighboring gene defensin beta 108B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. Cloutier P, et al. PLoS Genet, 2013. PMID 23349634, Free PMC Article
    2. Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514
    3. A proteome-scale map of the human interactome network. Rolland T, et al. Cell, 2014 Nov 20. PMID 25416956, Free PMC Article
    4. A reference map of the human binary protein interactome. Luck K, et al. Nature, 2020 Apr. PMID 32296183, Free PMC Article
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Other Names

    • family with sequence similarity 86, member C
    • protein FAM86C1

    Clone Names

    • FLJ10661, FLJ27199, MGC45068

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      71787514..71799661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_004643250.2 RNA Sequence

      Related
      ENST00000675931.1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      71714420..71726582
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_007082281.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001099653.1: Suppressed sequence

      Description
      NM_001099653.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    2. NM_018172.3: Suppressed sequence

      Description
      NM_018172.3: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    3. NM_152563.2: Suppressed sequence

      Description
      NM_152563.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NVL1.3 GenPept UniProtKB/Swiss-Prot:Q9NVL1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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