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    Acbd4 acyl-Coenzyme A binding domain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 67131, updated on 17-Feb-2024

    Summary

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    Official Symbol
    Acbd4provided by MGI
    Official Full Name
    acyl-Coenzyme A binding domain containing 4provided by MGI
    Primary source
    MGI:MGI:1914381
    See related
    Ensembl:ENSMUSG00000056938 AllianceGenome:MGI:1914381
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010009P05Rik; 2010015A21Rik
    Summary
    Is expressed in liver and liver lobe. Orthologous to human ACBD4 (acyl-CoA binding domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: suggests misassembly
    Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
    Expression
    Broad expression in duodenum adult (RPKM 33.3), subcutaneous fat pad adult (RPKM 30.6) and 23 other tissues See more
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    Genomic context

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    See Acbd4 in Genome Data Viewer
    Location:
    11 E1; 11 66.71 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (102992524..103003026)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (103101688..103112199)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene N-myristoyltransferase 1 Neighboring gene predicted gene, 42090 Neighboring gene phospholipase C, delta 3 Neighboring gene STARR-seq mESC enhancer starr_30831 Neighboring gene STARR-positive B cell enhancer ABC_E204 Neighboring gene STARR-positive B cell enhancer ABC_E4004 Neighboring gene STARR-positive B cell enhancer ABC_E738 Neighboring gene hexamethylene bis-acetamide inducible 1 Neighboring gene hexamethylene bis-acetamide inducible 2 Neighboring gene STARR-positive B cell enhancer ABC_E379

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. Timmermans S, et al. JCI Insight, 2018 Jul 12. PMID 29997285, Free PMC Article
    2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    acyl-CoA-binding domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025988.3 → NP_080264.1  acyl-CoA-binding domain-containing protein 4

      See identical proteins and their annotated locations for NP_080264.1

      Status: VALIDATED

      Source sequence(s)
      AL731805, BB863821
      UniProtKB/TrEMBL
      A2AHR2, Q80X94
      Conserved Domains (1) summary
      pfam00887
      Location:11 → 91
      ACBP; Acyl CoA binding protein

    RNA

    1. NR_169793.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL731805
      Related
      ENSMUST00000107040.10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      102992524..103003026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001081495.1: Suppressed sequence

      Description
      NM_001081495.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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