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    Zbtb47 zinc finger and BTB domain containing 47 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316087, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Zbtb47provided by RGD
    Official Full Name
    zinc finger and BTB domain containing 47provided by RGD
    Primary source
    RGD:1562434
    See related
    Ensembl:ENSRNOG00000019382 AllianceGenome:RGD:1562434
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp651; RGD1562434
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZBTB47 (zinc finger and BTB domain containing 47). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 129.5), Heart (RPKM 86.6) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zbtb47 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (130300255..130311874)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (121420758..121434365)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (130397984..130409437)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene SS18 like 2 Neighboring gene natural killer cell triggering receptor Neighboring gene kelch-like family member 40 Neighboring gene hedgehog acyltransferase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and BTB domain containing 47; zinc finger and BTB domain-containing protein 47
    Names
    zinc finger protein 651

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430552.1 → NP_001417481.1  zinc finger and BTB domain containing 47 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      D3ZQI7

    2. NM_001430553.1 → NP_001417482.1  zinc finger and BTB domain containing 47 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    3. NM_001430554.1 → NP_001417483.1  zinc finger and BTB domain containing 47 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      130300255..130311874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244166.5 → XP_006244228.1  zinc finger and BTB domain-containing protein 47 isoform X3

      See identical proteins and their annotated locations for XP_006244228.1

      Conserved Domains (6) summary
      smart00225
      Location:18 → 113
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:613 → 662
      COG5048; FOG: Zn-finger [General function prediction only]
      TIGR04104
      Location:560 → 604
      cxxc_20_cxxc; cxxc_20_cxxc protein
      sd00017
      Location:561 → 581
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:4 → 110
      BTB; BTB/POZ domain
      pfam13465
      Location:629 → 652
      zf-H2C2_2; Zinc-finger double domain

    2. XM_008766708.3 → XP_008764930.1  zinc finger and BTB domain-containing protein 47 isoform X3

      Conserved Domains (6) summary
      smart00225
      Location:18 → 113
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:613 → 662
      COG5048; FOG: Zn-finger [General function prediction only]
      TIGR04104
      Location:560 → 604
      cxxc_20_cxxc; cxxc_20_cxxc protein
      sd00017
      Location:561 → 581
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:4 → 110
      BTB; BTB/POZ domain
      pfam13465
      Location:629 → 652
      zf-H2C2_2; Zinc-finger double domain

    3. XM_006244168.5 → XP_006244230.2  zinc finger and BTB domain-containing protein 47 isoform X1

      Conserved Domains (6) summary
      PLN03086
      Location:486 → 560
      PLN03086; PRLI-interacting factor K; Provisional
      COG5048
      Location:694 → 743
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:636 → 719
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:642 → 662
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18231
      Location:82 → 195
      BTB_POZ_ZBTB47_ZNF651; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 47 (ZBTB47)
      pfam15471
      Location:212 → 269
      TMEM171; Transmembrane protein family 171

    4. XM_006244165.5 → XP_006244227.1  zinc finger and BTB domain-containing protein 47 isoform X2

      Related
      ENSRNOP00000041105.5
      Conserved Domains (6) summary
      smart00225
      Location:46 → 141
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:641 → 690
      COG5048; FOG: Zn-finger [General function prediction only]
      TIGR04104
      Location:588 → 632
      cxxc_20_cxxc; cxxc_20_cxxc protein
      sd00017
      Location:589 → 609
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:32 → 138
      BTB; BTB/POZ domain
      pfam13465
      Location:657 → 680
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. XR_005488597.2 RNA Sequence

    2. XR_005488596.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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