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    Mospd3 motile sperm domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 68929, updated on 5-Mar-2024

    Summary

    Official Symbol
    Mospd3provided by MGI
    Official Full Name
    motile sperm domain containing 3provided by MGI
    Primary source
    MGI:MGI:1916179
    See related
    Ensembl:ENSMUSG00000037221 AllianceGenome:MGI:1916179
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    R124; Gtig2; 1190005J19Rik; 5133401H10Rik
    Summary
    Predicted to enable FFAT motif binding activity. Acts upstream of or within heart development. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. Orthologous to human MOSPD3 (motile sperm domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 55.5), thymus adult (RPKM 49.0) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    5 G2; 5 76.59 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137594907..137599342, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137596645..137601079, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene actin-like 6B Neighboring gene transferrin receptor 2 Neighboring gene STARR-positive B cell enhancer ABC_E2180 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:138038199-138038386 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:138041904-138042125 Neighboring gene STARR-positive B cell enhancer ABC_E281 Neighboring gene predicted gene 7285 Neighboring gene procollagen C-endopeptidase enhancer protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    motile sperm domain-containing protein 3
    Names
    gene trap integration gene 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001254762.1NP_001241691.1  motile sperm domain-containing protein 3

      See identical proteins and their annotated locations for NP_001241691.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC148018, AW050147, BQ445267, CK617131
      Consensus CDS
      CCDS19771.1
      UniProtKB/Swiss-Prot
      Q8BGG6
      UniProtKB/TrEMBL
      Q05DT5
      Related
      ENSMUSP00000106636.2, ENSMUST00000111007.8
      Conserved Domains (1) summary
      pfam00635
      Location:41133
      Motile_Sperm; MSP (Major sperm protein) domain
    2. NM_030037.2NP_084313.1  motile sperm domain-containing protein 3

      See identical proteins and their annotated locations for NP_084313.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC148018, AI845922, AK004495, AK019892, BE861793, DV656015
      Consensus CDS
      CCDS19771.1
      UniProtKB/Swiss-Prot
      Q8BGG6
      UniProtKB/TrEMBL
      Q05DT5
      Related
      ENSMUSP00000040828.8, ENSMUST00000037620.14
      Conserved Domains (1) summary
      pfam00635
      Location:41133
      Motile_Sperm; MSP (Major sperm protein) domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      137594907..137599342 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504613.5XP_006504676.1  motile sperm domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006504676.1

      Conserved Domains (1) summary
      pfam00635
      Location:41133
      Motile_Sperm; MSP (Major sperm protein) domain
    2. XM_006504614.5XP_006504677.1  motile sperm domain-containing protein 3 isoform X2

      See identical proteins and their annotated locations for XP_006504677.1

      UniProtKB/Swiss-Prot
      Q8BGG6
      UniProtKB/TrEMBL
      Q05DT5
      Conserved Domains (1) summary
      pfam00635
      Location:41133
      Motile_Sperm; MSP (Major sperm protein) domain
    3. XM_006504612.2XP_006504675.1  motile sperm domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006504675.1

      Conserved Domains (1) summary
      pfam00635
      Location:41133
      Motile_Sperm; MSP (Major sperm protein) domain