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    Iqcm IQ motif containing M [ Mus musculus (house mouse) ]

    Gene ID: 71831, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Iqcmprovided by MGI
    Official Full Name
    IQ motif containing Mprovided by MGI
    Primary source
    MGI:MGI:1919081
    See related
    Ensembl:ENSMUSG00000031620 AllianceGenome:MGI:1919081
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700007B14Rik
    Summary
    Is expressed in paramesonephric duct of female, mesonephric portion and paramesonephric duct of male, mesonephric portion. Orthologous to human IQCM (IQ motif containing M). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 8.9) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    8 C1; 8 35.65 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (76175322..76711136)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (75448687..75984508)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_21935 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase, retrotransposed 2 Neighboring gene predicted gene, 19885 Neighboring gene predicted gene, 57524 Neighboring gene STARR-seq mESC enhancer starr_21936 Neighboring gene STARR-seq mESC enhancer starr_21937 Neighboring gene STARR-seq mESC enhancer starr_21939 Neighboring gene 3-phosphoglycerate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_21940 Neighboring gene predicted gene, 22544 Neighboring gene STARR-seq mESC enhancer starr_21942 Neighboring gene predicted gene, 22509

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library. Choi E, et al. BMC Genomics, 2007 Jul 28. PMID 17662146, Free PMC Article
    2. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Georgas K, et al. Dev Biol, 2009 Aug 15. PMID 19501082
    3. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Sang L, et al. Cell, 2011 May 13. PMID 21565611, Free PMC Article
    4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC143580, MGC143581

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    IQ domain-containing protein M

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164235.1 → NP_001157707.1  IQ domain-containing protein M

      See identical proteins and their annotated locations for NP_001157707.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC117750, AC118474, AC118721, AC119980, AC125177
      Consensus CDS
      CCDS52603.1
      UniProtKB/TrEMBL
      Q149I8, Q149I9
      Related
      ENSMUSP00000148495.2, ENSMUST00000212704.2

    2. NM_027944.1 → NP_082220.1  IQ domain-containing protein M

      See identical proteins and their annotated locations for NP_082220.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK005693, BC117768, BF153008
      Consensus CDS
      CCDS52603.1
      UniProtKB/TrEMBL
      Q149I8, Q149I9
      Related
      ENSMUSP00000034033.9, ENSMUST00000034033.15

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      76175322..76711136
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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