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    CG43163 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38966, updated on 10-May-2024

    Summary

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    Official Symbol
    CG43163provided by FlyBase
    Primary source
    FLYBASE:FBgn0262719
    Locus tag
    Dmel_CG43163
    See related
    AllianceGenome:FB:FBgn0262719
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6902; CG6915; Dmel\CG43163
    Old locus tag
    Dmel_CG6902; Dmel_CG6915
    Summary
    Is expressed in spermatozoon. Orthologous to human TTC28 (tetratricopeptide repeat domain 28). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG43163 in Genome Data Viewer
    Location:
    66D1-66D4; 3-26 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8472807..8507146, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8465907..8500246, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Grunge Neighboring gene ZC3H3 Neighboring gene Pseudouridine synthase 7 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide identification of Drosophila dorso-ventral enhancers by differential histone acetylation analysis. Koenecke N, et al. Genome Biol, 2016 Sep 27. PMID 27678375, Free PMC Article
    2. Unraveling the Genetic Basis for the Rapid Diversification of Male Genitalia between Drosophila Species. Hagen JFD, et al. Mol Biol Evol, 2021 Jan 23. PMID 32931587, Free PMC Article
    3. The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster. Jehrke L, et al. Sci Rep, 2018 Apr 18. PMID 29670218, Free PMC Article
    4. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article
    5. Protein interaction mapping: a Drosophila case study. Formstecher E, et al. Genome Res, 2005 Mar. PMID 15710747, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c8490928-8481828 mobile_element_type = transposon:roo{}958
    • Loc: c8505761-8498352 mobile_element_type = transposon:blood{}959

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG43163-PC
    CG43163-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      8472807..8507146 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139971.2 → NP_648228.2  uncharacterized protein Dmel_CG43163, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648228.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSK6
      Conserved Domains (8) summary
      smart00028
      Location:884 → 914
      TPR; Tetratricopeptide repeats
      COG0457
      Location:467 → 752
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:98 → 128
      TPR; TPR repeat [structural motif]
      pfam03546
      Location:1957 → 2287
      Treacle; Treacher Collins syndrome protein Treacle
      pfam12770
      Location:1421 → 1718
      CHAT; CHAT domain
      pfam13176
      Location:643 → 677
      TPR_7; Tetratricopeptide repeat
      pfam13414
      Location:101 → 164
      TPR_11; TPR repeat
      pfam13424
      Location:1044 → 1112
      TPR_12; Tetratricopeptide repeat

    2. NM_001259744.1 → NP_001246673.1  uncharacterized protein Dmel_CG43163, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246673.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSK6
      Conserved Domains (8) summary
      smart00028
      Location:884 → 914
      TPR; Tetratricopeptide repeats
      COG0457
      Location:467 → 752
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:98 → 128
      TPR; TPR repeat [structural motif]
      pfam03546
      Location:1957 → 2287
      Treacle; Treacher Collins syndrome protein Treacle
      pfam12770
      Location:1421 → 1718
      CHAT; CHAT domain
      pfam13176
      Location:643 → 677
      TPR_7; Tetratricopeptide repeat
      pfam13414
      Location:101 → 164
      TPR_11; TPR repeat
      pfam13424
      Location:1044 → 1112
      TPR_12; Tetratricopeptide repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VSK6 Q9VSK6

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