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    Txndc9 thioredoxin domain containing 9 [ Mus musculus (house mouse) ]

    Gene ID: 98258, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Txndc9provided by MGI
    Official Full Name
    thioredoxin domain containing 9provided by MGI
    Primary source
    MGI:MGI:2138153
    See related
    Ensembl:ENSMUSG00000058407 AllianceGenome:MGI:2138153
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    APACD
    Summary
    Predicted to be involved in microtubule cytoskeleton organization. Located in several cellular components, including centrosome; midbody; and nucleus. Orthologous to human TXNDC9 (thioredoxin domain containing 9). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 11.2), placenta adult (RPKM 8.5) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Txndc9 in Genome Data Viewer
    Location:
    1 B; 1 16.37 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (38022385..38036324, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (37983867..37997294, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene lysozyme G-like 2 Neighboring gene STARR-seq mESC enhancer starr_00687 Neighboring gene lysozyme G-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E3269 Neighboring gene STARR-positive B cell enhancer ABC_E10006 Neighboring gene eukaryotic translation initiation factor 5B Neighboring gene STARR-seq mESC enhancer starr_00688 Neighboring gene predicted gene, 34448 Neighboring gene STARR-seq mESC enhancer starr_00689 Neighboring gene STARR-seq mESC enhancer starr_00690 Neighboring gene REV1, DNA directed polymerase Neighboring gene STARR-seq mESC enhancer starr_00691

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Txndc9 Is Required for Meiotic Maturation of Mouse Oocytes. Ma F, et al. Biomed Res Int, 2017. PMID 28626760, Free PMC Article
    2. An evolutionarily conserved gene required for proper microtubule architecture in Caenorhabditis elegans. Ogawa S, et al. Genes Cells, 2004 Feb. PMID 15009089
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in midbody IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thioredoxin domain-containing protein 9
    Names
    ATP binding protein associated with cell differentiation

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001417936.1 → NP_001404865.1  thioredoxin domain-containing protein 9 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC114583
      UniProtKB/Swiss-Prot
      Q3TKD2, Q9CQ79
      Related
      ENSMUSP00000141609.2, ENSMUST00000195247.6

    2. NM_001417937.1 → NP_001404866.1  thioredoxin domain-containing protein 9 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC114583
      UniProtKB/Swiss-Prot
      Q3TKD2, Q9CQ79
      Related
      ENSMUSP00000141595.2, ENSMUST00000195032.6

    3. NM_001417938.1 → NP_001404867.1  thioredoxin domain-containing protein 9 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC114583
      UniProtKB/TrEMBL
      A0A0A6YXY0
      Related
      ENSMUSP00000142188.2, ENSMUST00000193832.6

    4. NM_001417939.1 → NP_001404868.1  thioredoxin domain-containing protein 9 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC114583
      UniProtKB/TrEMBL
      A0A0A6YVV3
      Related
      ENSMUSP00000141281.2, ENSMUST00000192960.6

    5. NM_001417940.1 → NP_001404869.1  thioredoxin domain-containing protein 9 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC114583
      UniProtKB/TrEMBL
      A0A0A6YVV3

    6. NM_001417941.1 → NP_001404870.1  thioredoxin domain-containing protein 9 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC114583
      UniProtKB/TrEMBL
      A0A0A6YVV3

    7. NM_172054.5 → NP_742051.1  thioredoxin domain-containing protein 9 isoform a

      See identical proteins and their annotated locations for NP_742051.1

      Status: VALIDATED

      Source sequence(s)
      AC114583
      Consensus CDS
      CCDS14898.1
      UniProtKB/Swiss-Prot
      Q3TKD2, Q9CQ79
      Related
      ENSMUSP00000125491.2, ENSMUST00000162031.8
      Conserved Domains (1) summary
      cd02989
      Location:68 → 180
      Phd_like_TxnDC9; Phosducin (Phd)-like family, Thioredoxin (TRX) domain containing protein 9 (TxnDC9) subfamily; composed of predominantly uncharacterized eukaryotic proteins, containing a TRX-like domain without the redox active CXXC motif. The gene name for the human ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      38022385..38036324 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CQ79.1 GenPept UniProtKB/Swiss-Prot:Q9CQ79

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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