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    Vmn2r25 vomeronasal 2, receptor 25 [ Mus musculus (house mouse) ]

    Gene ID: 545874, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Vmn2r25provided by MGI
    Official Full Name
    vomeronasal 2, receptor 25provided by MGI
    Primary source
    MGI:MGI:3644645
    See related
    Ensembl:ENSMUSG00000094672 AllianceGenome:MGI:3644645
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG545874
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vmn2r25 in Genome Data Viewer
    Location:
    6 F2; 6 58.87 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (123799773..123830149, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (123822814..123853190, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor 24 Neighboring gene STARR-seq mESC enhancer starr_17280 Neighboring gene myeloid cell leukemia sequence 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_17281 Neighboring gene predicted gene, 23079 Neighboring gene STARR-seq mESC enhancer starr_17282 Neighboring gene STARR-seq mESC enhancer starr_17283 Neighboring gene STARR-seq mESC enhancer starr_17284 Neighboring gene STARR-seq mESC enhancer starr_17285 Neighboring gene synaptotagmin binding, cytoplasmic RNA interacting protein pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E6485 Neighboring gene vomeronasal 2, receptor 26 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal receptor Vmn2r25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104641.1 → NP_001098111.1  vomeronasal receptor Vmn2r25 precursor

      See identical proteins and their annotated locations for NP_001098111.1

      Status: INFERRED

      Source sequence(s)
      AC140330
      Consensus CDS
      CCDS51903.1
      UniProtKB/TrEMBL
      W4VSP2
      Related
      ENSMUSP00000124342.2, ENSMUST00000162046.3
      Conserved Domains (4) summary
      cd06365
      Location:38 → 511
      PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam00003
      Location:606 → 840
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:83 → 451
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:521 → 571
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      123799773..123830149 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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