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    Fhad1 forkhead-associated phosphopeptide binding domain 1 [ Mus musculus (house mouse) ]

    Gene ID: 329977, updated on 7-Apr-2024

    Summary

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    Official Symbol
    Fhad1provided by MGI
    Official Full Name
    forkhead-associated phosphopeptide binding domain 1provided by MGI
    Primary source
    MGI:MGI:1920323
    See related
    Ensembl:ENSMUSG00000051435 AllianceGenome:MGI:1920323
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B230311F11; 2900090M10Rik
    Summary
    Is expressed in central nervous system and olfactory epithelium. Orthologous to human FHAD1 (forkhead associated phosphopeptide binding domain 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 39.2) and lung adult (RPKM 2.2) See more
    Orthologs
    human all
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    Genomic context

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    See Fhad1 in Genome Data Viewer
    Location:
    4 D3; 4 74.75 cM
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (141617741..141742438, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (141890430..142015127, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene EF hand domain containing 2 Neighboring gene forkhead-associated phosphopeptide binding domain 1, opposite strand 2 Neighboring gene predicted gene, 46874 Neighboring gene predicted gene, 42338 Neighboring gene predicted gene, 35295 Neighboring gene STARR-positive B cell enhancer mm9_chr4:141508770-141509070 Neighboring gene forkhead-associated phosphopeptide binding domain 1, opposite strand 1 Neighboring gene RIKEN cDNA 4930455G09 gene Neighboring gene STARR-positive B cell enhancer ABC_E10274 Neighboring gene transmembrane protein 51 Neighboring gene STARR-seq mESC enhancer starr_11942 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:141636026-141636227 Neighboring gene Tmem51 opposite strand 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation. Carmona-Mora P, et al. Hum Genet, 2015 Oct. PMID 26275350
    2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Forkhead-associated phosphopeptide binding domain 1 (FHAD1) deficiency impaired murine sperm motility.
      Title: Forkhead-associated phosphopeptide binding domain 1 (FHAD1) deficiency impaired murine sperm motility.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    forkhead-associated domain-containing protein 1
    Names
    FHA domain-containing protein 1
    forkhead-associated (FHA) phosphopeptide binding domain 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177868.4 → NP_808536.2  forkhead-associated domain-containing protein 1

      See identical proteins and their annotated locations for NP_808536.2

      Status: VALIDATED

      Source sequence(s)
      AL645731, AL663037
      Consensus CDS
      CCDS51349.1
      UniProtKB/Swiss-Prot
      A2AAC3, A6PWD2, Q3UFH8, Q8BLA4, Q8CHV8, Q9CUV2
      Related
      ENSMUSP00000101405.3, ENSMUST00000105779.9
      Conserved Domains (3) summary
      COG1196
      Location:286 → 937
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR03354
      Location:19 → 159
      VI_FHA; type VI secretion system FHA domain protein
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      141617741..141742438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320274.2 → XP_017175763.1  forkhead-associated domain-containing protein 1 isoform X11

      Conserved Domains (2) summary
      COG1196
      Location:286 → 925
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    2. XM_030253621.1 → XP_030109481.1  forkhead-associated domain-containing protein 1 isoform X6

      Conserved Domains (2) summary
      COG1196
      Location:324 → 1015
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    3. XM_030253618.1 → XP_030109478.1  forkhead-associated domain-containing protein 1 isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:324 → 1015
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    4. XM_030253617.1 → XP_030109477.1  forkhead-associated domain-containing protein 1 isoform X1

      Conserved Domains (2) summary
      COG1196
      Location:324 → 1015
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    5. XM_030253620.1 → XP_030109480.1  forkhead-associated domain-containing protein 1 isoform X4

      Conserved Domains (3) summary
      COG1196
      Location:286 → 977
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR03354
      Location:19 → 159
      VI_FHA; type VI secretion system FHA domain protein
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    6. XM_017320272.1 → XP_017175761.1  forkhead-associated domain-containing protein 1 isoform X8

      Conserved Domains (2) summary
      COG1196
      Location:262 → 899
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    7. XM_017320269.1 → XP_017175758.1  forkhead-associated domain-containing protein 1 isoform X5

      Conserved Domains (2) summary
      COG1196
      Location:324 → 975
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    8. XM_030253625.1 → XP_030109485.1  forkhead-associated domain-containing protein 1 isoform X13

      Conserved Domains (3) summary
      COG1196
      Location:324 → 1015
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02463
      Location:713 → 1368
      SMC_N; RecF/RecN/SMC N terminal domain
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    9. XM_030253624.2 → XP_030109484.1  forkhead-associated domain-containing protein 1 isoform X12

      Conserved Domains (2) summary
      COG1196
      Location:324 → 1015
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    10. XM_030253623.2 → XP_030109483.1  forkhead-associated domain-containing protein 1 isoform X10

      Conserved Domains (2) summary
      COG1196
      Location:324 → 1015
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    11. XM_017320279.1 → XP_017175768.1  forkhead-associated domain-containing protein 1 isoform X14

      Conserved Domains (3) summary
      PTZ00121
      Location:640 → 1258
      PTZ00121; MAEBL; Provisional
      COG1196
      Location:262 → 899
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    12. XM_006538956.5 → XP_006539019.1  forkhead-associated domain-containing protein 1 isoform X9

      See identical proteins and their annotated locations for XP_006539019.1

      UniProtKB/Swiss-Prot
      A2AAC3, A6PWD2, Q3UFH8, Q8BLA4, Q8CHV8, Q9CUV2
      Related
      ENSMUSP00000101406.2, ENSMUST00000105780.8
      Conserved Domains (3) summary
      COG1196
      Location:286 → 937
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR03354
      Location:19 → 159
      VI_FHA; type VI secretion system FHA domain protein
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    13. XM_030253619.2 → XP_030109479.1  forkhead-associated domain-containing protein 1 isoform X3

      Conserved Domains (2) summary
      COG1196
      Location:324 → 1015
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    14. XM_030253622.2 → XP_030109482.1  forkhead-associated domain-containing protein 1 isoform X7

      Conserved Domains (2) summary
      COG1196
      Location:324 → 1015
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    15. XM_036164201.1 → XP_036020094.1  forkhead-associated domain-containing protein 1 isoform X15

      Conserved Domains (2) summary
      COG1196
      Location:262 → 889
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    16. XM_017320280.3 → XP_017175769.1  forkhead-associated domain-containing protein 1 isoform X16

      Conserved Domains (3) summary
      TIGR02168
      Location:326 → 737
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR03354
      Location:55 → 197
      VI_FHA; type VI secretion system FHA domain protein
      pfam00498
      Location:18 → 122
      FHA; FHA domain

    RNA

    1. XR_003954977.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_028429.1: Suppressed sequence

      Description
      NM_028429.1: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6PWD2.1 GenPept UniProtKB/Swiss-Prot:A6PWD2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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