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    GAGE5 G antigen 5 [ Homo sapiens (human) ]

    Gene ID: 2577, updated on 10-Oct-2023

    Summary

    Official Symbol
    GAGE5provided by HGNC
    Official Full Name
    G antigen 5provided by HGNC
    Primary source
    HGNC:HGNC:4102
    See related
    MIM:300598
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CT4.5
    Summary
    This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
    Annotation information
    Annotation category: not annotated on reference assembly
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    Genomic context

    See GAGE5 in Genome Data Viewer
    Location:
    Xp11.4-p11.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (48810109..48817380)

    Chromosome X - NC_060947.1Genomic Context describing neighboring genes Neighboring gene G antigen 7-like Neighboring gene G antigen 7-like Neighboring gene G antigen 5 Neighboring gene G antigen 7-like

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_060947.1 Chromosome X Alternate T2T-CHM13v2.0

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    G antigen 5
    Names
    GAGE-5
    cancer/testis antigen 4.5
    cancer/testis antigen family 4, member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001475.1NP_001466.1  G antigen 5

      See identical proteins and their annotated locations for NP_001466.1

      Status: REVIEWED

      Source sequence(s)
      U19146
      UniProtKB/Swiss-Prot
      Q13069, Q6FG72
      UniProtKB/TrEMBL
      B7ZVY3
      Conserved Domains (1) summary
      pfam05831
      Location:1111
      GAGE; GAGE protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      48810109..48817380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)