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    Zfp385c zinc finger protein 385C [ Mus musculus (house mouse) ]

    Gene ID: 278304, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Zfp385cprovided by MGI
    Official Full Name
    zinc finger protein 385Cprovided by MGI
    Primary source
    MGI:MGI:3608347
    See related
    Ensembl:ENSMUSG00000014198 AllianceGenome:MGI:3608347
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf385c; A930006D11Rik
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be active in nucleus. Orthologous to human ZNF385C (zinc finger protein 385C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 25.5), large intestine adult (RPKM 12.2) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    11 D; 11 63.47 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (100517045..100583292, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (100626219..100692466, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:100443371-100443554 Neighboring gene 2',3'-cyclic nucleotide 3' phosphodiesterase Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene STARR-positive B cell enhancer ABC_E4000 Neighboring gene STARR-positive B cell enhancer ABC_E7061 Neighboring gene STARR-positive B cell enhancer ABC_E2369 Neighboring gene STARR-positive B cell enhancer ABC_E7062 Neighboring gene NFKB inhibitor interacting Ras-like protein 2 Neighboring gene chromosome 11 C17orf113 homolog Neighboring gene predicted gene, 38483 Neighboring gene STARR-positive B cell enhancer ABC_E7063 Neighboring gene STARR-positive B cell enhancer ABC_E9843 Neighboring gene DExH-box helicase 58 Neighboring gene K(lysine) acetyltransferase 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 385C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001373887.1 → NP_001360816.1  zinc finger protein 385C isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Conserved Domains (4) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:311 → 379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:378 → 445
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:379 → 402
      zf-met; Zinc-finger of C2H2 type

    2. NM_001373888.1 → NP_001360817.1  zinc finger protein 385C isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Conserved Domains (4) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:310 → 378
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:377 → 444
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:378 → 401
      zf-met; Zinc-finger of C2H2 type

    3. NM_001373889.1 → NP_001360818.1  zinc finger protein 385C isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Conserved Domains (3) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:311 → 379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:379 → 402
      zf-met; Zinc-finger of C2H2 type

    4. NM_001373890.1 → NP_001360819.1  zinc finger protein 385C isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Conserved Domains (3) summary
      sd00020
      Location:231 → 299
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:298 → 365
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:299 → 322
      zf-met; Zinc-finger of C2H2 type

    5. NM_177790.4 → NP_808458.2  zinc finger protein 385C isoform 5

      See identical proteins and their annotated locations for NP_808458.2

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Consensus CDS
      CCDS25430.1
      UniProtKB/Swiss-Prot
      A2A5E6, Q14AS5, Q8C8X1
      Related
      ENSMUSP00000099408.4, ENSMUST00000103119.10
      Conserved Domains (3) summary
      sd00020
      Location:230 → 298
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:297 → 364
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:298 → 321
      zf-met; Zinc-finger of C2H2 type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      100517045..100583292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246059.1 → XP_030101919.1  zinc finger protein 385C isoform X3

      Conserved Domains (4) summary
      smart00451
      Location:103 → 132
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:369 → 437
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:436 → 503
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:437 → 460
      zf-met; Zinc-finger of C2H2 type

    2. XM_030246056.1 → XP_030101916.1  zinc finger protein 385C isoform X2

      Conserved Domains (4) summary
      smart00451
      Location:132 → 161
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:397 → 465
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:464 → 531
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:465 → 488
      zf-met; Zinc-finger of C2H2 type

    3. XM_006533488.4 → XP_006533551.3  zinc finger protein 385C isoform X1

      Conserved Domains (4) summary
      smart00451
      Location:132 → 161
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:398 → 466
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:465 → 532
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:466 → 489
      zf-met; Zinc-finger of C2H2 type

    4. XM_006533492.5 → XP_006533555.1  zinc finger protein 385C isoform X4

      See identical proteins and their annotated locations for XP_006533555.1

      Conserved Domains (4) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:311 → 379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:378 → 445
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:379 → 402
      zf-met; Zinc-finger of C2H2 type

    5. XM_011249062.3 → XP_011247364.1  zinc finger protein 385C isoform X5

      Conserved Domains (3) summary
      sd00020
      Location:230 → 298
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:297 → 364
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:298 → 321
      zf-met; Zinc-finger of C2H2 type

    6. XM_006533496.4 → XP_006533559.1  zinc finger protein 385C isoform X6

      Conserved Domains (3) summary
      sd00020
      Location:178 → 246
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:245 → 312
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:246 → 269
      zf-met; Zinc-finger of C2H2 type
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2A5E6.1 GenPept UniProtKB/Swiss-Prot:A2A5E6

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