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    Catspere2 cation channel sperm associated auxiliary subunit epsilon 2 [ Mus musculus (house mouse) ]

    Gene ID: 545391, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Catspere2provided by MGI
    Official Full Name
    cation channel sperm associated auxiliary subunit epsilon 2provided by MGI
    Primary source
    MGI:MGI:5589632
    See related
    Ensembl:ENSMUSG00000091476 AllianceGenome:MGI:5589632
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm16432; Gm30473
    Summary
    Predicted to be located in sperm principal piece. Predicted to be part of CatSper complex. Orthologous to human CATSPERE (catsper channel auxiliary subunit epsilon). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 4.8), adrenal adult (RPKM 0.6) and 3 other tissues See more
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    Genomic context

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    See Catspere2 in Genome Data Viewer
    Location:
    1 H4; 1 82.87 cM
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (177810724..178000273)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (177983155..178172707)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4395 Neighboring gene STARR-positive B cell enhancer ABC_E632 Neighboring gene STARR-seq mESC enhancer starr_03135 Neighboring gene adenylosuccinate synthase 2 Neighboring gene ribosomal protein S8 pseudogene Neighboring gene cation channel sperm associated auxiliary subunit epsilon 1 Neighboring gene STARR-seq mESC enhancer starr_03137 Neighboring gene STARR-positive B cell enhancer ABC_E2589 Neighboring gene predicted gene, 25312 Neighboring gene STARR-seq mESC enhancer starr_03139 Neighboring gene STARR-positive B cell enhancer ABC_E4396 Neighboring gene translin-associated factor X pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr1:180115890-180116191 Neighboring gene STARR-positive B cell enhancer ABC_E2023 Neighboring gene desumoylating isopeptidase 2 Neighboring gene STARR-seq mESC enhancer starr_03140 Neighboring gene STARR-positive B cell enhancer mm9_chr1:180172365-180172665 Neighboring gene predicted gene 8023

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in flagellated sperm motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sperm capacitation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of CatSper complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in sperm principal piece IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in sperm principal piece ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cation channel sperm-associated protein subunit epsilon-like protein
    Names
    catSper-epsilon-like
    catSperepsilon-like
    catsper channel auxiliary subunit epsilon 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034899.3 → NP_001030071.2  cation channel sperm-associated protein subunit epsilon-like protein isoform b precursor

      See identical proteins and their annotated locations for NP_001030071.2

      Status: VALIDATED

      Source sequence(s)
      AK131684, BC147686
      Consensus CDS
      CCDS35802.1
      UniProtKB/TrEMBL
      A0A5F8MPD0
      Related
      ENSMUSP00000091828.5, ENSMUST00000094273.10

    2. NM_001368822.1 → NP_001355751.1  cation channel sperm-associated protein subunit epsilon-like protein isoform a precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes the longer isoform (a).
      Source sequence(s)
      AC113044, AC119928, AC124621
      Consensus CDS
      CCDS87931.1
      UniProtKB/TrEMBL
      A0A571BGH9
      Related
      ENSMUSP00000158854.2, ENSMUST00000238506.2
      Conserved Domains (1) summary
      pfam15020
      Location:729 → 956
      CATSPERD; Cation channel sperm-associated protein subunit delta

    RNA

    1. NR_155538.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC119928, AC124621, AK029617, BB616902
      Related
      ENSMUST00000192146.2

    2. NR_160909.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC113044, AC119928, AC124621
      Related
      ENSMUST00000239149.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      177810724..178000273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030255583.2 → XP_030111443.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X7

      Conserved Domains (1) summary
      pfam15020
      Location:552 → 779
      CATSPERD; Cation channel sperm-associated protein subunit delta

    2. XM_036152449.1 → XP_036008342.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X1

    3. XM_036152450.1 → XP_036008343.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X2

    4. XM_036152451.1 → XP_036008344.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X3

    5. XM_036152454.1 → XP_036008347.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X4

      UniProtKB/Swiss-Prot
      A0A0A6YXX9, B2RW93, Q3V2N6

    6. XM_036152456.1 → XP_036008349.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X5

      UniProtKB/Swiss-Prot
      A0A0A6YXX9, B2RW93, Q3V2N6

    7. XM_036152457.1 → XP_036008350.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X6

      UniProtKB/Swiss-Prot
      A0A0A6YXX9, B2RW93, Q3V2N6

    8. XM_036152458.1 → XP_036008351.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X8

      UniProtKB/Swiss-Prot
      A0A0A6YXX9, B2RW93, Q3V2N6

    9. XM_036152459.1 → XP_036008352.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X8

      UniProtKB/Swiss-Prot
      A0A0A6YXX9, B2RW93, Q3V2N6

    10. XM_036152460.1 → XP_036008353.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X9

    RNA

    1. XR_004933815.1 RNA Sequence

    2. XR_004933813.1 RNA Sequence

    3. XR_004933816.1 RNA Sequence

    4. XR_001785174.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0A6YXX9.1 GenPept UniProtKB/Swiss-Prot:A0A0A6YXX9

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