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    Or6z7 olfactory receptor family 6 subfamily Z member 7 [ Mus musculus (house mouse) ]

    Gene ID: 18349, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Or6z7provided by MGI
    Official Full Name
    olfactory receptor family 6 subfamily Z member 7provided by MGI
    Primary source
    MGI:MGI:106685
    See related
    Ensembl:ENSMUSG00000096228 AllianceGenome:MGI:106685
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr5; ORL120; MOR103-8
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or6z7 in Genome Data Viewer
    Location:
    7 A1; 7 3.76 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (6483215..6490013, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (6480216..6487014, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 6 subfamily Z member 3 Neighboring gene olfactory receptor family 6 subfamily Z member 5 Neighboring gene STARR-seq mESC enhancer starr_17980 Neighboring gene olfactory receptor family 6 subfamily Z member 6 Neighboring gene olfactory receptor family 6 subfamily Z member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Ressler KJ, et al. Cell, 1994 Dec 30. PMID 7528109
    2. The chromosomal distribution of mouse odorant receptor genes. Sullivan SL, et al. Proc Natl Acad Sci U S A, 1996 Jan 23. PMID 8570653, Free PMC Article
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC123608

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within detection of chemical stimulus involved in sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within response to stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 6Z7
    Names
    GA_x6K02T2QGBW-3210997-3210059
    odorant receptor M41
    olfactory receptor 103-8
    olfactory receptor 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146914.2 → NP_667125.1  olfactory receptor 6Z7

      See identical proteins and their annotated locations for NP_667125.1

      Status: VALIDATED

      Source sequence(s)
      AC188461
      Consensus CDS
      CCDS57479.1
      UniProtKB/Swiss-Prot
      Q3MI75, Q60889, Q8VGH4
      Related
      ENSMUSP00000083498.5, ENSMUST00000086318.5
      Conserved Domains (1) summary
      cd15224
      Location:30 → 298
      7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      6483215..6490013 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250453.3 → XP_011248755.1  olfactory receptor 6Z7 isoform X1

      See identical proteins and their annotated locations for XP_011248755.1

      UniProtKB/Swiss-Prot
      Q3MI75, Q60889, Q8VGH4
      Related
      ENSMUSP00000147586.3, ENSMUST00000209866.4
      Conserved Domains (1) summary
      cd15224
      Location:30 → 298
      7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q60889.2 GenPept UniProtKB/Swiss-Prot:Q60889

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