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Ankrd50 ankyrin repeat domain 50 [ Mus musculus (house mouse) ]

Gene ID: 99696, updated on 5-Mar-2024

Summary

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Official Symbol
Ankrd50provided by MGI
Official Full Name
ankyrin repeat domain 50provided by MGI
Primary source
MGI:MGI:2139777
See related
Ensembl:ENSMUSG00000044864 AllianceGenome:MGI:2139777
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1223; mKIAA3019; E430012K20Rik
Summary
Predicted to be involved in endocytic recycling. Orthologous to human ANKRD50 (ankyrin repeat domain 50). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 12.5), thymus adult (RPKM 11.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Ankrd50 in Genome Data Viewer
Location:
3 B; 3 18.49 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (38503408..38539005, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (38449259..38484862, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42213 Neighboring gene STARR-seq mESC enhancer starr_07447 Neighboring gene predicted gene, 36823 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 22 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2663 Neighboring gene STARR-seq mESC enhancer starr_07448 Neighboring gene STARR-seq mESC enhancer starr_07449 Neighboring gene STARR-seq mESC enhancer starr_07450 Neighboring gene STARR-seq mESC enhancer starr_07451 Neighboring gene ferritin light chain 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_07452 Neighboring gene predicted gene, 29879

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Clone Names

  • KIAA1223

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endocytic recycling ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 50
Names
ankrin repeat domain 50

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167883.1 → NP_001161355.1  ankyrin repeat domain-containing protein 50 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC127284
    Consensus CDS
    CCDS50897.1
    UniProtKB/TrEMBL
    D3Z643, Q6ZPE3
    Related
    ENSMUSP00000113349.2, ENSMUST00000120875.8
    Conserved Domains (1) summary
    pfam13191
    Location:23 → 195
    AAA_16; AAA ATPase domain

  2. NM_001373894.1 → NP_001360823.1  ankyrin repeat domain-containing protein 50 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC127284
    UniProtKB/TrEMBL
    F7BE84
    Conserved Domains (6) summary
    PHA02876
    Location:763 → 1102
    PHA02876; ankyrin repeat protein; Provisional
    PHA03095
    Location:625 → 907
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:676 → 707
    ANK; ANK repeat [structural motif]
    pfam15440
    Location:1225 → 1339
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
    pfam13191
    Location:23 → 195
    AAA_16; AAA ATPase domain
    cl27783
    Location:251 → 352
    Cas9_REC; REC lobe of CRISPR-associated endonuclease Cas9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    38503408..38539005 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006535582.5 → XP_006535645.1  ankyrin repeat domain-containing protein 50 isoform X1

    See identical proteins and their annotated locations for XP_006535645.1

    UniProtKB/TrEMBL
    F7BE84
    Related
    ENSMUSP00000122842.2, ENSMUST00000156038.2
    Conserved Domains (6) summary
    PHA02876
    Location:763 → 1102
    PHA02876; ankyrin repeat protein; Provisional
    PHA03095
    Location:625 → 907
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:676 → 707
    ANK; ANK repeat [structural motif]
    pfam15440
    Location:1225 → 1339
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
    pfam13191
    Location:23 → 195
    AAA_16; AAA ATPase domain
    cl27783
    Location:251 → 352
    Cas9_REC; REC lobe of CRISPR-associated endonuclease Cas9

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001033198.2: Suppressed sequence

    Description
    NM_001033198.2: This RefSeq was temporarily suppressed because the CDS was partial.
Nucleotide Protein Strain
Heading Accession and Version

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