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Mrpl27 mitochondrial ribosomal protein L27 [ Mus musculus (house mouse) ]

Gene ID: 94064, updated on 5-Mar-2024

Summary

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Official Symbol
Mrpl27provided by MGI
Official Full Name
mitochondrial ribosomal protein L27provided by MGI
Primary source
MGI:MGI:2137224
See related
Ensembl:ENSMUSG00000024414 AllianceGenome:MGI:2137224
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D11Moh47; D18Ertd643e; A630055F16Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; genitourinary system; heart; and liver. Orthologous to human MRPL27 (mitochondrial ribosomal protein L27). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 13.1), kidney adult (RPKM 10.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 D; 11 58.9 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (94544593..94552758)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (94653770..94661932)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene STARR-seq mESC enhancer starr_30470 Neighboring gene chondroadherin Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:94452878-94453079 Neighboring gene STARR-seq mESC enhancer starr_30472 Neighboring gene STARR-positive B cell enhancer mm9_chr11:94490883-94491183 Neighboring gene leucine rich repeat containing 59 Neighboring gene essential meiotic structure-specific endonuclease 1 Neighboring gene xylosyltransferase II Neighboring gene STARR-positive B cell enhancer ABC_E8444 Neighboring gene predicted gene 11541

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level. Mohlke KL, et al. Genomics, 1998 Nov 15. PMID 9806826
  2. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069
  3. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  4. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  5. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within translation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein bL27m
Names
39S ribosomal protein L27, mitochondrial
L27mt
MRP-L27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053161.2 → NP_444391.1  large ribosomal subunit protein bL27m

    See identical proteins and their annotated locations for NP_444391.1

    Status: PROVISIONAL

    Source sequence(s)
    BC030074
    Consensus CDS
    CCDS25263.1
    UniProtKB/Swiss-Prot
    Q99N92
    Related
    ENSMUSP00000025278.8, ENSMUST00000025278.8
    Conserved Domains (1) summary
    pfam01016
    Location:31 → 101
    Ribosomal_L27; Ribosomal L27 protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    94544593..94552758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534567.3 → XP_006534630.1  large ribosomal subunit protein bL27m isoform X1

    See identical proteins and their annotated locations for XP_006534630.1

    Conserved Domains (1) summary
    cl00359
    Location:11 → 57
    Ribosomal_L27; Ribosomal L27 protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99N92.1 GenPept UniProtKB/Swiss-Prot:Q99N92

Gene LinkOut

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