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Dqx1 DEAQ RNA-dependent ATPase [ Mus musculus (house mouse) ]

Gene ID: 93838, updated on 11-Apr-2024

Summary

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Official Symbol
Dqx1provided by MGI
Official Full Name
DEAQ RNA-dependent ATPaseprovided by MGI
Primary source
MGI:MGI:2136388
See related
Ensembl:ENSMUSG00000009145 AllianceGenome:MGI:2136388
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310066E11Rik
Summary
Predicted to enable ATP hydrolysis activity and RNA binding activity. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is expressed in thymus primordium. Orthologous to human DQX1 (DEAQ-box RNA dependent ATPase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in duodenum adult (RPKM 21.5), large intestine adult (RPKM 21.4) and 16 other tissues See more
Orthologs
human all
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Genomic context

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Location:
6 C3; 6 35.94 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83034728..83044294)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83057747..83067313)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lysyl oxidase-like 3 Neighboring gene microRNA 7040 Neighboring gene STARR-positive B cell enhancer ABC_E9275 Neighboring gene HtrA serine peptidase 2 Neighboring gene ancient ubiquitous protein 1 Neighboring gene T cell leukemia, homeobox 2 Neighboring gene polycomb group ring finger 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. DQX1, an RNA-dependent ATPase homolog with a novel DEAQ box: expression pattern and genomic sequence comparison of the human and mouse genes. Ji W, et al. Mamm Genome, 2001 Jun. PMID 11353393
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ATP-dependent RNA helicase DQX1
Names
DEAQ box polypeptide 1
NP_291084.1
XP_006506870.1
XP_006506871.1
XP_006506872.1
XP_006506873.1
XP_006506874.1
XP_036008306.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033606.3 → NP_291084.1  ATP-dependent RNA helicase DQX1

    See identical proteins and their annotated locations for NP_291084.1

    Status: PROVISIONAL

    Source sequence(s)
    AC104324
    Consensus CDS
    CCDS20268.1
    UniProtKB/Swiss-Prot
    Q80ZJ5, Q924H9
    Related
    ENSMUSP00000076708.3, ENSMUST00000077502.5
    Conserved Domains (1) summary
    COG1643
    Location:9 → 672
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    83034728..83044294
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506808.3 → XP_006506871.1  ATP-dependent RNA helicase DQX1 isoform X1

    See identical proteins and their annotated locations for XP_006506871.1

    UniProtKB/Swiss-Prot
    Q80ZJ5, Q924H9
    Conserved Domains (1) summary
    COG1643
    Location:9 → 672
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

  2. XM_006506810.5 → XP_006506873.1  ATP-dependent RNA helicase DQX1 isoform X2

    Conserved Domains (1) summary
    COG1643
    Location:9 → 648
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

  3. XM_006506807.5 → XP_006506870.1  ATP-dependent RNA helicase DQX1 isoform X1

    See identical proteins and their annotated locations for XP_006506870.1

    UniProtKB/Swiss-Prot
    Q80ZJ5, Q924H9
    Conserved Domains (1) summary
    COG1643
    Location:9 → 672
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

  4. XM_006506811.5 → XP_006506874.1  ATP-dependent RNA helicase DQX1 isoform X3

    Conserved Domains (1) summary
    COG1643
    Location:1 → 567
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

  5. XM_036152413.1 → XP_036008306.1  ATP-dependent RNA helicase DQX1 isoform X4

    Conserved Domains (1) summary
    COG1643
    Location:8 → 390
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

  6. XM_006506809.2 → XP_006506872.1  ATP-dependent RNA helicase DQX1 isoform X1

    See identical proteins and their annotated locations for XP_006506872.1

    UniProtKB/Swiss-Prot
    Q80ZJ5, Q924H9
    Conserved Domains (1) summary
    COG1643
    Location:9 → 672
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

RNA

  1. XR_004933648.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q924H9.1 GenPept UniProtKB/Swiss-Prot:Q924H9

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