MILIP MYC inducible lncRNA inactivating p53 [Homo sapiens (human)] - Gene

Summary

Official Symbol: MILIPprovided by HGNC
Official Full Name: MYC inducible lncRNA inactivating p53provided by HGNC
Primary source: HGNC:HGNC:43649
See related: Ensembl:ENSG00000265688 AllianceGenome:HGNC:43649
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: MAFG-DT; MAFG-AS1
Expression: Broad expression in testis (RPKM 2.2), thyroid (RPKM 0.6) and 19 other tissues See more
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Genomic context

Location:: 17q25.3

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	17	NC_000017.11 (81927829..81930753)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	17	NC_060941.1 (82794988..82797912)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	17	NC_000017.10 (79885705..79888629)

Chromosome 17 - NC_000017.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Long non-coding RNA MAFG-AS1: A promising therapeutic target for human cancers.
Title: Long non-coding RNA MAFG-AS1: A promising therapeutic target for human cancers.
A review on the roles and molecular mechanisms of MAFG-AS1 in oncogenesis.
Title: A review on the roles and molecular mechanisms of MAFG-AS1 in oncogenesis.
LncRNA MAFG-AS1-induced acute myeloid leukemia development via modulating miR-147b/HOXA9.
Title: LncRNA MAFG-AS1-induced acute myeloid leukemia development via modulating miR-147b/HOXA9.
MAFG-AS1/MAFG positive feedback loop contributes to cisplatin resistance in bladder urothelial carcinoma through antagonistic ferroptosis.
Title: MAFG-AS1/MAFG positive feedback loop contributes to cisplatin resistance in bladder urothelial carcinoma through antagonistic ferroptosis.
The N-Myc-responsive lncRNA MILIP promotes DNA double-strand break repair through non-homologous end joining.
Title: The N-Myc-responsive lncRNA MILIP promotes DNA double-strand break repair through non-homologous end joining.
lncRNA MAFGAS1 enhances radioresistance of glioblastoma cells via miR642a5p/Notch1 axis.
Title: lncRNA MAFG‑AS1 enhances radioresistance of glioblastoma cells via miR‑642a‑5p/Notch1 axis.
LncRNA MILIP links YBX1 to translational activation of Snai1 and promotes metastasis in clear cell renal cell carcinoma.
Title: LncRNA MILIP links YBX1 to translational activation of Snai1 and promotes metastasis in clear cell renal cell carcinoma.
LncRNA MAFG-AS1 deregulated in breast cancer affects autophagy and progression of breast cancer by interacting with miR-3612 and FKBP4 invitro.
Title: LncRNA MAFG-AS1 deregulated in breast cancer affects autophagy and progression of breast cancer by interacting with miR-3612 and FKBP4 invitro.
LncRNA MAFG-AS1 promotes the malignant phenotype of ovarian cancer by upregulating NFKB1-dependent IGF1.
Title: LncRNA MAFG-AS1 promotes the malignant phenotype of ovarian cancer by upregulating NFKB1-dependent IGF1.
Regulatory effect of the MAFGAS1/miR1505p/MYB axis on the proliferation and migration of breast cancer cells.
Title: Regulatory effect of the MAFG‑AS1/miR‑150‑5p/MYB axis on the proliferation and migration of breast cancer cells.

Submit: New GeneRIF Correction See all GeneRIFs (17)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

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General gene information

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Other Names

MAFG antisense RNA 1 (head to head)
MAFG antisense RNA 1 (non-protein coding)
MAFG divergent transcript
c-Myc-Inducible Long noncoding RNA Inactivating P53

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.